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OpenTrials
Completed

NCT Number: NCT00080158

Treatment of Adolescent Suicide Attempters (TASA)

The purpose of this study is to compare the effects of three types of treatments for depressed teenagers who have attempted suicide.

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Key information

Conditions

Depression Behavior Behavioral Symptoms Depressive Disorder Dysthymic Disorder Mental Disorders Mood Disorders Self-Injurious Behavior Suicide Suicide, Attempted

Age range

12 year–18 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2 / Phase 3

Primary location

Johns Hopkins University, Baltimore, Maryland, United States

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About this study

Suicide is the third leading cause of death in adolescents and is a major public health problem. Depression is the most common diagnosis for adolescent suicide attempts. Little is known about what treatment is best for these adolescents since they are usually excluded from participation in research studies.

Participants in this study will be randomly assigned to receive carefully monitored antidepressant medication with routine support and management, cognitive behavioral therapy (CBT), or a combination of antidepressant medication plus CBT.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • At least one suicide attempt or interrupted attempt within the past 45 days
  • Continuously reside with a primary caretaker (parent, legal guardian, foster parent) for at least 6 months that can provide legal consent

Treatment and study plan

Fluoxetine

Drug

Sertraline

Drug

Citalopram

Drug

Escitalopram

Drug

bupropion

Drug

mirtazapine

Drug

Venlafaxine

Drug

Lithium

Drug

Cognitive behavioral therapy

Behavioral

Sponsors and collaborators

Lead sponsor

New York State Psychiatric Institute

Other

Collaborators

  • National Institute of Mental Health (NIMH)

Registry information

Important dates

Study start
2004
Study completion
2007
First posted
Mar 26, 2004
Registry last updated
Jun 22, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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