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Completed

NCT Number: NCT00764400

Treatment for Word Retrieval Impairments in Aphasia

In this study the investigators are examining the effectiveness of two different speech therapy protocols for word retrieval impairments experienced by individuals with stroke-induced aphasia. One treatment involves errorless naming treatment and the other employs verbal plus gestural facilitation of word retrieval. Participants will receive one of the two treatments over several months. Before and after treatment the investigators will administer several tests and conversational samples to examine changes associated with the treatments. The investigators hypothesize that, whereas both treatments will lead to improvements in words rehearsed in therapy, communication outcomes in conversation will be broader for the verbal plus gestural protocol.

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Key information

Conditions

Stroke Anomia Aphasia Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Communication Disorders Language Disorders Mental Disorders Nervous System Diseases Neurobehavioral Manifestations Neurodevelopmental Disorders Neurologic Manifestations Pathological Conditions, Signs and Symptoms Signs and Symptoms Speech Disorders Vascular Diseases

Age range

21 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Old Dominion University Speech and Hearing Clinic

Norfolk, Virginia, 23529, United States

About this study

In this study the investigators are examining the effectiveness of two different speech therapy protocols for word retrieval impairments experienced by individuals with stroke-induced aphasia. One treatment involves errorless naming treatment and the other employs verbal plus gestural facilitation of word retrieval. Participants will receive one of the two treatments over several months. Before and after treatment the investigators will administer several tests and conversational samples to examine changes associated with the treatments. The investigators hypothesize that, whereas both treatments will lead to improvements in words rehearsed in therapy, communication outcomes in conversation will be broader for the verbal plus gestural protocol.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • left hemisphere stroke >4 months earlier
  • aphasia with word retrieval impairments
  • >21 years of age right handed
  • speaker of English as the preferred language
  • >6 grade education

Exclusion criteria

  • history of developmental learning difficulties
  • history of prior neurological illnesses
  • chronic medical illnesses that restrict participation in speech therapy
  • alcohol or drug dependence
  • severe uncorrected impairments of vision or hearing

Treatment and study plan

Word Retrieval Treatments for Aphasia

Behavioral

Speech therapy sessions take place 4 times per week for up to 90 minutes per session. Following a phase of baseline pre-testing, two phases of speech therapy will take place lasting up to 20 sessions per phase. Post-testing will take place immediately upon completion of the treatment phases and again at 1 month post study completion.

Primary outcomes

  1. Daily Probe Picture Naming

    Time frame: daily probes from three times per week for up to 3 months and one month posttreatment

Secondary outcomes

  1. Western Aphasia Battery

    Time frame: pre-treatment and at treatment completion

  2. Boston Naming Test

    Time frame: pretreatment and at treatment completion

  3. Discourse Sample

    Time frame: pre-treatment and at treatment completion

Sponsors and collaborators

Lead sponsor

Old Dominion University

Other

Collaborators

  • National Institute on Deafness and Other Communication Disorders (NIDCD)

Registry information

Official study title

Communication Outcomes for Naming Treatments in Aphasia

Important dates

Study start
2008
Primary completion
2013
Study completion
2013
First posted
Oct 2, 2008
Registry last updated
Apr 6, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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