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OpenTrials
Completed

NCT Number: NCT00194948

Treatment Choices for Improving Adherence and Outcome

This study will determine the effectiveness of offering primary care patients their preferred treatment versus one that is less desirable in improving treatment adherence and outcome.

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Key information

Conditions

Major Depression Depressive Disorder Depressive Disorder, Major Mental Disorders Mood Disorders

Age range

21 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Cornell Internal Medicine Associates, New York, United States

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About this study

This study investigates whether offering primary care patients treatment that is congruent with their preferred first choice improves adherence and outcomes, in comparison to offering treatment that is not congruent with their preferred first choice. All subjects are offered a treatment with demonstrated efficacy, namely either the antidepressant medication escitalopram or Interpersonal Psychotherapy for 5 months. We hypothesize that patients who receive congruent treatment will be more likely to initiate treatment, adhere to treatment, and achieve depression remission.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age 21-99
  • English-speaking
  • DSM-IV criteria for major depression

Exclusion criteria

  • unable to give informed consent
  • MMSE<24
  • DSM-IV diagnosis of bipolar disorder, psychotic disorder, current alcohol or substance abuse
  • active suicide ideation
  • aphasia
  • acute or severe medical illness
  • currently receiving either antidepressant medication or psychotherapy

Treatment and study plan

Escitalopram

Drug

interpersonal psychotherapy

Behavioral

Primary outcomes

  1. treatment initiation

  2. treatment adherence

Secondary outcomes

  1. depressive symptomatology

Sponsors and collaborators

Lead sponsor

Weill Medical College of Cornell University

Other

Collaborators

  • National Institute of Mental Health (NIMH)

Registry information

Official study title

Patient Preference in Primary Care Depression Treatment

Important dates

Study start
2003
Primary completion
2007
Study completion
2007
First posted
Sep 19, 2005
Registry last updated
Nov 4, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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