Treadmill Training and Quality of Life in Parkinson's Disease

Parkinson's disease (PD) causes motor and non-motor impairments that affect the quality of life of the subjects. The purpose was to assess the effects of treadmill walking training with additional body load on the quality of life and motor symptoms of the subjects with PD.

Methods: Nine subjects with PD, Hoehn and Yahr stages 2 through 3, not demented and with capability to ambulate independently voluntarily participate in this study. The training program was divided into three phases (A1-B-A2): treadmill training with additional body load (A1), control condition (conventional physical therapy group) (B) and treadmill training with load again (A2). Each phase lasted six weeks. The quality of life and motor symptoms were assessed by PDQ-39 and UPDRS, respectively. Both evaluations and training were performed during on-phase of the medication cycle.

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Key information

Conditions

Parkinson's Disease Basal Ganglia Diseases Brain Diseases Central Nervous System Diseases Movement Disorders Nervous System Diseases Neurodegenerative Diseases Parkinson Disease Parkinsonian Disorders Synucleinopathies

Age range

51 year–81 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Universidade Federal de São Carlos

São Carlos, São Paulo, 13565-905, Brazil

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Hoehn and Yahr (H-Y) stages 2 through 3
Absence of dementia (Mini-Mental Status Examination - MMSE, defined according to educational level)
Capacity to ambulate independently for at least 10 meters

Exclusion criteria

Change medication (dopaminergic) during the study period
Use treadmill for at least six months prior to the study
Other neurologic problems or musculoskeletal, cardiovascular and respiratory disease or uncorrected visual deficit that could represent risk and interfere in the accomplishment of the training

Treatment and study plan

Treadmill walking training with additional body load

Other

The training program was divided into three phases (A1-B-A2):

treadmill training with additional body load (A1),
control condition (conventional physical therapy group) (B). and
treadmill training with additional body load again (A2).

Each phase lasted six weeks, totaling 18 weeks. Both evaluations and training were performed during on-phase of the medication cycle.

Primary outcomes

The quality of life was measured through Parkinson Disease Questionnaire (PDQ-39).

Time frame: 4 times, once before treatment, and 3 after each treatment phase.

Sponsors and collaborators

Lead sponsor

Universidade Federal de Sao Carlos

Other

Registry information

Official study title

Treadmill Walking Training With Additional Body Load Improves Quality of Life in Subjects With Parkinson's Disease

Important dates

Study start: 2007
Study completion: 2008
First posted: Apr 30, 2009
Registry last updated: May 4, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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