Suicidal behaviors among adolescents are a major public health issue. Traumatic exposure (sexual abuse, violence, serious accidents) is a recognized risk factor for psychopathology and suicidality, but its precise links with suicide recurrence, comorbid psychopathology, and neurodevelopmental vulnerability remain little studied.
Hypotheses:
- Traumatic exposure is more common among suicidal adolescents than non-suicidal.
- It is associated with an increased risk of recurrence within 6 months.
- The neurodevelopmental load, irritability, PTSD and lack of resilience factors modulate this risk.
- Specific inflammatory biological profiles could be associated with suicidality.
Originality and innovative aspects:
- Multidimensional approach: clinical, psychometric, biological and qualitative.
- Constitution of a biobank for future analyses (inflammatory, genetic, epigenetic).
- Inclusion of a qualitative component exploring the subjective experience of hospitalized adolescents.
- Integrated analysis of risk, protective and biological factors to guide personalized prevention.
The main objective is to compare the frequency of traumatic exposure history evaluated with the validated questionnaire in French of the CPC version child, among adolescents aged between 11 years old and 17 years inclusive admitted to hospital, either for suicidal behaviors (suicide group), either for other psychiatric causes without a history of suicidal behavior (non-suicidal group).