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Completed

NCT Number: NCT04591119

Transversus Thoracis Muscle Plane Block for Postoperative Pain in Adult Cardiac Surgery

Inadequate pain control after coronary artery bypass graft surgery increases mortality and results in a higher incidence of persistent poststernotomy pain syndrome. Our aim is to assess whether ultrasound-guided parasternal intercostal block (PSIB) or surgeon implied transversus thoracic muscle plane block (TTMPB) would improve the postoperative pain scores and decrease tramadol consumption better after coronary artery bypass graft surgery

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Key information

Conditions

Postoperative Pain Chest Pain Coronary Artery Bypass Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms Sternotomy

Age range

45 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Mugla Sıtkı Kocman University Training nad research Hospital

Muğla, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • American Society of Anesthesiologists physical status II-III
  • Elective coronary artery bypass graft surgery under general anesthesia

Exclusion criteria

  • American Society of Anesthesiologists physical status IV
  • Emergency surgery and redo surgery
  • Low cardiac output syndrome, perioperative intra-aortic balloon pump support for any reason, bleeding disorder or abnormal coagulation profile, abnormal hepatic and renal parameters, uncontrolled diabetes mellitus, chronic obstructive pulmonary disease, atrial fibrillation on anticoagulation
  • Allergy to any study drugs, local infection at the block site
  • Opioid abuse

Treatment and study plan

Transversus Thoracic Muscle Plane Block

Procedure

40 ml %0.375 bupivacaine divided into 4 equal doses will be injected by the surgeon between internal intercostal muscle and transversus thoracis muscle at the 2nd and 3rd intercostal space and 4th and 5th intercostal space

Parasternal Intercostal Plane Block

Procedure

40 ml %0.375 bupivacaine injection will be performed by ultrasound guidance after completion of surgery between pectoralis major muscle and external intercostal muscle at the 2nd and 3rd intercostal space and 4th and 5th intercostal space bilaterally by anesthesiologist.

Primary outcomes

  1. Postoperative opioid consumption

    Time frame: Postoperative 24th hour

    Tramadol consumption will be assessed by checking patient daily drug order records

  2. Postoperative opioid consumption

    Time frame: Postoperative 1st, 4th and 12th hour

    Tramadol consumption will be assessed by checking patient daily drug order records

Secondary outcomes

  1. Behavioral Pain Scale

    Time frame: postoperative 1st and 4th hour

    A blinded nurse will assess postoperative pain while they are intubated at the 1st and 4th hour by using 3 subscale Behavioral Pain Scale which ranges from 3 (no pain) to 12 (maximum pain)

  2. Numeric Rating Scale

    Time frame: Postoperative 12th and 24th hour

    A blinded nurse will assess postoperative pain during resting and movement at postoperative 12th and 24th hour by using Numeric rating scale at the extubated patient by using 11-point Numerical Rating Scale which ranges from '0' (means no pain) to '10' (means worst pain imaginable)

Sponsors and collaborators

Lead sponsor

Muğla Sıtkı Koçman University

Other

Registry information

Official study title

Bilateral Transversus Thoracis Muscle Plane Block for Acute Postoperative Pain in Adult Coronary Artery Bypass Graft Surgery: A Randomized Controlled Observer Blinded Trial

Important dates

Study start
2020
Primary completion
2020
Study completion
2020
First posted
Oct 19, 2020
Registry last updated
Dec 5, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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