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Completed

NCT Number: NCT02645903

Transversus Abdominis Plane Block for Postoperative Analgesia in Living Donor Hepatectomy

Living donor organ transplantation has increased in recent years due to an increased need for organs. The objective of this study was to investigate the effects of a TAP block on postoperative analgesia and opioid consumption in liver transplantation donors in whom a right lateral extending upper mid-line abdominal incision was used.

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Key information

Conditions

Acute Pain Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

About this study

This prospective randomized controlled double-blinded study was conducted with 50 liver transplantation donors between 18-65 years who were scheduled to undergo right hepatectomy surgery. Cases to whom TAP block with ultrasound was applied after standard general anesthesia were determined as Group 1 and cases to whom only standard general anesthesia was applied, were determined as Group 2.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Liver transplantation donors

Exclusion criteria

  • Patients with a history of allergy to the drugs used in the study protocol, coagulation pathology, opioid tolerance

Treatment and study plan

Transversus Abdominis Plane Block

Drug

Cases to whom used bupivacaine with ultrasound guided transversus abdominis plane block was applied after standard general anesthesia were determined as Group 1

Other names: Marcaine plain+morphine

standard general anesthesia

Drug

Cases to whom applied alone standard general anesthesia were determined as Group 2

Other names: morphine

Primary outcomes

  1. pain scores (at movement and at rest)

    Time frame: postoperatively at 24 hours

    Pain scores were assessed using a visual analog scale (0: No pain, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10: Excruciating pain).

Secondary outcomes

  1. morphine consumption

    Time frame: postoperatively at 24 hours

    morphine consumption were measured in postoperatively 24 hours

Sponsors and collaborators

Lead sponsor

Inonu University

Other

Registry information

Official study title

Ultrasound-guided Transversus Abdominis Plane Block for Postoperative Analgesia in Living Donor Hepatectomy: Randomized Controlled Double-blinded Trial

Important dates

Study start
2015
Primary completion
2015
Study completion
2015
First posted
Jan 5, 2016
Registry last updated
Jan 6, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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