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NCT Number: NCT07624916

Transversus Abdominis Plane and Rectus Sheath Block for Robotic Colectomy

This study aimed to evaluate the impact of ultrasound-guided bilateral transversus abdominis plane block combined with rectus sheath block on postoperative pain and recovery after robotic colectomy under an enhanced recovery after surgery (ERAS) protocol.

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Key information

About this study

Postoperative pain remains an important concern after robotic colectomy despite the implementation of enhanced recovery after surgery (ERAS) protocols. Although robotic colectomy is associated with smaller incisions and faster recovery than conventional open surgery, postoperative pain may still impair early ambulation, gastrointestinal recovery, and patient satisfaction. Multimodal analgesia strategies, including acetaminophen and nonsteroidal anti-inflammatory drugs, are commonly used in ERAS pathways to reduce opioid consumption and opioid-related adverse effects. However, postoperative pain during movement and opioid requirements remain clinically relevant issues.

Ultrasound-guided transversus abdominis plane (TAP) block has been reported to reduce postoperative pain and opioid consumption after colorectal surgery. In addition, rectus sheath block (RSB) may provide further analgesic benefit for midline abdominal incision pain. Nevertheless, the additional clinical benefit of combining TAP block and RSB in patients undergoing robotic colectomy within an established ERAS pathway has not been fully investigated.

This study aimed to evaluate the impact of ultrasound-guided bilateral TAP block combined with RSB on postoperative pain and recovery following robotic colectomy. Additionally, we investigated the influence of TAP block combined with RSB on postoperative opioid consumption, postoperative nausea and vomiting, early ambulation, gastrointestinal recovery, and length of hospital stay after robotic colectomy under ERAS management.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients scheduled for elective robotic colorectal cancer surgery for the first time

Exclusion criteria

  • Age < 18 years or age > 80 years
  • Allergic to any medication in the protocol
  • Infection over the injection site
  • Chronic pain history
  • Severe hepatic or renal insufficiency
  • Pregnancy
  • Emergency surgery
  • Refusal to join the study

Treatment and study plan

Ropivacaine

Drug

TAP+RS block using ropivacaine

Saline

Drug

TAP+RS block with saline

Primary outcomes

  1. Visual Analogue Scale at Resting

    Time frame: Postoperative 48 hours

  2. Visual Analogue Scale at Movement

    Time frame: Postoperative 48 hours

  3. Postoperative Opioid Consumption

    Time frame: Postoperative 48 hours

Secondary outcomes

  1. Postoperative Adverse Event

    Time frame: From surgery until hospital discharge

  2. Time to First Ambulation

    Time frame: From surgery until hospital discharge

  3. Time to First Flatus

    Time frame: From surgery until hospital discharge

  4. Hospital Stay

    Time frame: At hospital discharge

Study contacts

Contact information is provided by the study sponsor or research team.

Wei-Cheng Tseng, MD

CONTACT

[email protected]

886-2-8792-3311 ext. 24159

Sponsors and collaborators

Lead sponsor

Tri-Service General Hospital (TSGH)

Other

Registry information

Official study title

Impact of Transversus Abdominis Plane Block Combined With Rectus Sheath Block on Postoperative Pain Management in Patients Undergoing Elective Robotic Colectomy

Important dates

Study start
2026
Primary completion
2028
Study completion
2028
First posted
Jun 3, 2026
Registry last updated
Jun 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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