Skip to main content
OpenTrials
Completed

NCT Number: NCT02122510

Transverse Abdominal Block for Analgesia in Casarean Section

In this study, the investigators will compare the analgesic effect of bupivacaine and bupivacaine-dexmetomedine after elective cesarean delivery by performing an bilateral TAP block, on the patients for whom the operation will be performed under general anesthesia.

Completed

Looking for future studies?

Notify Me

Key information

Age range

21 year–40 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Tanta University Hospitals

Tanta, Algharbiya, 355217, Egypt

About this study

The investigators will study 60 ASA [American Society of Anesthesiologist] physical status I and ІІ patients undergoing elective cesarean delivery at tanta University Hospital, in a prospective, randomized, comparative, clinical trial.

Patients will be randomly allocated to two equal groups (n = 30) using closed envelopes labeled 1,and 2 reflecting group 1and 2 respectively.

The drugs are prepared by the anesthesiologist who is not involved in the study or data collection.

Group I: (n=30) will receive pre-delivery bilateral TAP block with 10 ml of bupivacaine 0.5 % mixed with 10 ml saline and 10 μg dexmetonedine in 20 ml syringe labeled G 2.

Group II: (n=30) will receive post-delivery bilateral TAP block with 10 ml of bupivacaine 0.5 % mixed with 10 ml saline in 20 ml syringe labeled G2.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • We will study 60 ASA [American Society of Anesthesiologist] physical status I and ІІ patients undergoing elective cesarean delivery
  • Age between 21-40 years old.

Exclusion criteria

  • Refusal of participation in the study
  • Patients who have infection or tumor at the site of puncture for local anesthetic injection.
  • Patients who have coagulopathy, platelet abnormalities, and concurrent treatment with anticoagulant drugs.
  • Patients known to have allergy or sensitivity to dexmetomedine, and/or bupivacaine
  • Severe hepatic and/or renal insufficiency
  • Morbid obesity (body mass index (BMI) >35)
  • Psychological disease

Treatment and study plan

Bupivacine group

Drug

Bupivacaine group(n=30) will receive post-delivery bilateral TAP block with 10 ml of bupivacaine 0.5 % mixed with 10 ml saline and 10 μg dexmetonedine in 20 ml syringe

Other names: Bucaine

Dexmedetomidine

Drug

Dexamedtomedine group will receive post-delivery bilateral TAP block with 10 ml of bupivacaine 0.5 % mixed with 10 ml saline and 10 μg dexmetonedine in 20 ml syringe

Other names: precdex

Primary outcomes

  1. hemodynamic changes

    Time frame: 2 hours

    blood pressure and heart rate measured every 15 minutes during the intraopertive peroid

Secondary outcomes

  1. Analgesic requirements

    Time frame: 24 hours

    VAS will be measured during 24 hours after surgery every 4 hours

Sponsors and collaborators

Lead sponsor

Tanta University

Other

Registry information

Official study title

The Value of Preemptive Dexmedetomidine Transversus Abdominis Plane (TAP) Block in Patients Undergoing Elective Cesarean Section Under General Anesthesia.

Important dates

Study start
2013
Primary completion
2014
Study completion
2014
First posted
Apr 24, 2014
Registry last updated
Dec 16, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.