Stanford Hospital and Clinics
Stanford, California, 94305, United States
NCT Number: NCT03091179
The purpose of this study is to investigate whether selected, short laryngologic surgical procedures can be safely and potentially more effectively performed without the use of endotracheal tube or jet ventilation, under completely tubeless conditions. The patient's gas exchange will be supported by rapid insufflation of high-flow oxygen through specialized nasal cannulae: the so called Transnasal Humidified Rapid- Insufflation Ventilatory Exchange (THRIVE).
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Notify Me18 year–80 year
All sexes
Interventional
Not applicable
Stanford, California, 94305, United States
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
active nasal oxygen delivery system
a plastic tube for mechanical ventilation
Time frame: intraoperative (up to one hour)
Time frame: intraoperative (up to 20 min)
time from end of surgery to responding to commands/extubation
Time frame: intraoperative (up to 5 min)
Time required for the surgeon to position the patient's head and expose the surgical field for surgery using operating laryngoscope
Time frame: intraoperative (up to 5 min)
Number of attempts required for the surgeon to reposition the patient's head for optimal surgical exposure using operating laryngoscope
Time frame: intraoperative (up to one hour)
Time frame: Recovery room admission (up to 30 min following admission to recovery room)
Time required for the patient to become fully alert and oriented per standard recovery room evaluation
Time frame: Up to 2 hours after procedure
Time frame: Recovery room admission and discharge (up to 2 hours)
A score from 0 to 10, higher scores corresponding to higher pain
Time frame: Recovery room admission and discharge (up to 2 hours)
Total oral opioid consumption in morphine milligram equivalents
Time frame: Preoperative assessment and one month after surgery
numerical scale, range from 0 to 40, with higher scores corresponding to worse outcome
Time frame: One week after surgery
15-question survey, with each question scored from 0 to 10. Overall range 0-150, higher scores correspond to better outcome.
Stanford University
Other
The Safety and Efficacy of the Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) for Short Laryngologic Surgical Procedures.
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.