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NCT Number: NCT05091645

Translation and Cultural Adaptation of the Groningen Frailty Indicator (GFI) in Patients With Hip Fracture

This study attempts to the translation and the cultural adaptation of the Groningen Frailty Indicator (GFI) questionnaire in the Greek population in patients suffering from hip fracture.

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Key information

Age range

65 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Thessaly

Larissa, 41335, Greece

Location status: Recruiting

Location contact

Eleni Arnaoutoglou, MD, PhD

CONTACT

[email protected]

+306974301352

Eleni Arnaoutoglou, MD, PhD

PRINCIPAL_INVESTIGATOR

Fragkiskos Angelis, MD, M.Sc.

PRINCIPAL_INVESTIGATOR

Maria Ntalouka, MD, PhD

CONTACT

[email protected]

+306973688099

Maria Ntalouka, MD, PhD, M.Sc.

PRINCIPAL_INVESTIGATOR

Michael Hantes, MD, PhD

PRINCIPAL_INVESTIGATOR

About this study

Frailty indicates a state of vulnerability in terms of poor health outcomes, such as mortality, hospitalization, institutionalization and loss of function in one or more domains (i.e. physical, psychological, cognitive and social domains). Frailty is not only associated with poor quality of life and life satisfaction but also has an effect on health care demands, as the number of frail people in our aging population will increase.

Current literature suggests that frailty is a common condition among elderly patients with hip fracture. Ageing has been associated with a decline in physiological reserves which impedes the body's ability to withstand and recover from minor and major challenges, such as the hip fracture. Hence, accurate diagnosis of frailty seems mandatory. The Groningen Frailty Indicator (GFI) questionnaire is a feasible, reliable and valid self-assessment tool.

This study will provide the first official Greek translation and cultural adaptation of the GFI according to the ISPOR (International Society for Pharmacoeconomics and Outcomes Research) guidelines.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adult patients over 65 years old with hip fractures undergoing surgery
  • an ASA (American Society of Anesthesiologists) PS (physical status) I to III
  • non-institutionalized
  • able to communicate orally or in writing
  • consent to participate

Exclusion criteria

  • refused to participate
  • pathological hip fractures
  • institutionalized
  • patients with hip fracture treated conservatively
  • patients with severe cognitive dysfunction
  • patients with insufficient knowledge of the Greek language

Treatment and study plan

GFI

Other

Two trained raters who will be blinded and will have no access to each other's evaluation, will administer the GFI questionnaire within 24 hours of patients' hospital admission.

Primary outcomes

  1. Translation and Cultural adaptation of the Greek version of Groningen Frailty Indicator (GFI) questionnaire

    Time frame: Within 24 hours of the hospital admission

    Translation and Cultural adaptation of the Greek version of GFI

Secondary outcomes

  1. Incidence of frailty syndrome

    Time frame: Baseline (On admission)

    Incidence of frailty syndrome in our study sample

Study contacts

Contact information is provided by the study sponsor or research team.

Eleni Arnaoutoglou, MD, PhD

CONTACT

[email protected]

+306974301352

Maria Ntalouka, MD, PhD, MSc

CONTACT

[email protected]

+306973688099

Sponsors and collaborators

Lead sponsor

University of Thessaly

Other

Registry information

Official study title

Translation and Cultural Adaptation of the Greek Version of the Groningen Frailty Indicator (GFI) in Patients With Hip Fracture; a Prospective Cohort Study

Acronym: Gr-GFI

Important dates

Study start
2022
Primary completion
2026
Study completion
2026
First posted
Oct 25, 2021
Registry last updated
May 7, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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