Efficacy and Safety of Longidaze in the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia
NCT06568718
Genital Diseases, Genital Diseases, Male
Krasnodar, Russia
View Trial DetailsNCT Number: NCT01108367
In men, urinary incontinence (UI) is relatively uncommon, and usually associated with some forms of prostate surgery. Thus, one of the risks of surgery for benign prostate hyperplasia (BPH) is postoperative UI. The guidelines of the American Urological Association for BPH treatment indicate that UI (2~5%) is relevant complications after transurethral prostatectomy (TURP). Rassweiler et al., based on a review of publications stated that early UI may occur in up to 30-40% of patients after TURP. Rigatti et al. reported that early postoperative urgency UI occurred in 38.6% (TURP) and 44% (holmium laser enucleation of the prostate; HoLEP) of surgically treated patients at 1-month after the surgery. Recently, the follow-up data for patients treated with HoLEP showed that transient stress UI developed in up to 44% after HoLEP. Although this alternative surgical treatment such as HoLEP can be performed safely with minimal complications, patients often face debilitating UI during the postoperative period before any improvement in micturition parameters occurs. Although this symptom ameliorates within a relatively short time, it usually cause significant stress and anxiety to the patient as far as their durations is concerned. In addition to its economic cost, UI is a distressing condition that has major impacts on a patient's quality of life. Social withdrawal, isolation, and depression occur in some patients.
Because this problem is usually temporary, there has been little attempt at addressing the issue. Therefore, there has been no research devoted specifically to transient de novo UI associated with HoLEP.
1. The aim of the present study was following:
1. to investigate the incidence of transient de novo UI after HoLEP for BPH 2. determine the predictors of early postoperative transient de novo UI.
Looking for future studies?
Notify Me50 year and older
Male
Observational
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Seoul National University Hospital
Other
Predictor of Transient Urinary Incontinence Following Holmium Laser Enucleation of the Prostate
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06568718
Genital Diseases, Genital Diseases, Male
Krasnodar, Russia
View Trial DetailsNCT06699563
Genital Diseases, Genital Diseases, Male
Tekirdağ, Turkey (Türkiye)
View Trial DetailsNCT06995963
Genital Diseases, Genital Diseases, Male
Gonesse, France
View Trial DetailsNCT03228485
Genital Diseases, Genital Diseases, Male
Larissa, Greece
View Trial Details