Transcranial Direct Current Stimulation (tDCS) for Treatment of Negative Syndrome in Patients With Schizophrenia

Transcranial direct current stimulation (tDCS) showed beneficial effects on cognition in healthy subjects and depressed patients. In this study, patients with treatment resistant negative syndrome in schizophrenia will be treated with direct current stimulation. fMRI measures will be performed.

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Key information

Conditions

Schizophrenia Mental Disorders Schizophrenia Spectrum and Other Psychotic Disorders

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Klinik fuer Psychiatrie

Munich, 80336, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

schizophrenic patients with a negative syndrome. PANSS > 40.

Exclusion criteria

other psychiatric or neurologic diseases.

Treatment and study plan

eldith DC-stimulator (neuroconn, Ilmenau, Germany)

Device

daily tDCS treatment over left DLPFC, 20 min, 2 mA

Primary outcomes

SANS reduction

Time frame: 4 weeks after baseline

decrease by 30%

Secondary outcomes

neuropsychological tests

Time frame: 4 weeks after baseline

increase in SOPT by 30% increase in TMT by 30%

Sponsors and collaborators

Lead sponsor

Ludwig-Maximilians - University of Munich

Other

Registry information

Important dates

Study start: 2011
Primary completion: 2013
Study completion: 2013
First posted: Jun 22, 2011
Registry last updated: Jul 22, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed