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Completed

NCT Number: NCT00695708

Training-induced Cerebral Reorganization in Schizophrenia

The purpose of this study is to reveal the effects of computer-aided cognitive-auditory training on cerebral reorganization in schizophrenia.

Completed

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Key information

Conditions

Schizophrenia Cognition Disorders Cognitive Dysfunction Mental Disorders Neurocognitive Disorders Schizophrenia Spectrum and Other Psychotic Disorders

Age range

Up to 60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Konstanz

Konstanz, Baden Württenberg, 78457, Germany

About this study

Impairment in cognitive functions is one of the main symptoms in schizophrenia and is currently one of the challenges in the treatment of the disease.

In this study we compare effects of two computer-aided training programs. One focused on auditory perception and processing as a basic ability underlying higher order information processing.

The other training involves a variability of cognitive abilities.

Both trainings are computer-aided and time-intensive, including up to twenty sessions within four weeks.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Clinical diagnosis of schizophrenia and disorders with psychotic features
  • Intact hearing abilities

Exclusion criteria

  • Mental retardation
  • Age over 60
  • Insufficient German language knowledge

Treatment and study plan

Brain Fitness Program

Behavioral

Computer-aided cognitive program designed for intensive training of auditory perception, memory and attention

Cogpack

Behavioral

Computer-aided cognitive program for cognitive abilities

Primary outcomes

  1. Event related potential MEG, test scores in word fluency and verbal learning tasks

    Time frame: pre and post intervention

Secondary outcomes

  1. Symptom severity, GAF score

    Time frame: pre and post intervention

Sponsors and collaborators

Lead sponsor

University of Konstanz

Other

Collaborators

  • German Research Foundation

Registry information

Important dates

Study start
2008
Primary completion
2009
Study completion
2010
First posted
Jun 12, 2008
Registry last updated
Apr 13, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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