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OpenTrials
Completed

NCT Number: NCT07059533

Training in Combination With Non-invasive Brain Stimulation

The goal of this study is to investigate the impact of non-invasive brain stimulation on motor skill acquisition in healthy individuals. Participants performed a motor task with non-invasive brain stimulation applied over the area of the brain where movements were controlled. The study compared motor skill performance between with the active stimulation and the placebo stimulation.

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Key information

Conditions

Motor Skill Acquisition in Healthy Older Adults

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Campus Biotech

Geneva, Canton of Geneva, 1202, Switzerland

About this study

This study implemented a randomized, double-blinded, and sham-controlled design, investigating the effects of non-invasive brain stimulation on motor skill acquisition in healthy individuals.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age equals to or over 18 years old
  • absence of major neurological, psychiatric and physical impairment, with normal or corrected to normal vision
  • right handed
  • in good general health

Exclusion criteria

  • professional musicians/stenotypist
  • unable to consent
  • unable to perform the task as required (instructions and setup)
  • exclusion criteria for magnetic resonance imaging (MRI), transcranial electrical stimulation (tES), transcranial magnetic stimulation (TMS)

Treatment and study plan

Verum

Other

anodal transcranial direct current stimulation: 20 minutes of stimulation with 1 mA (ramp-up/ramp-down times of 8 seconds)

Placebo

Other

anodal transcranial direct current stimulation with 40 seconds of stimulation delivered at the beginning of training (with 8 seconds ramp-up and 5 seconds ramp-down times)

Primary outcomes

  1. Motor performance

    Time frame: From the start of the practice to the end of training at 5 days (and follow up on the 10th day and 60th day)

    Replication of a nine-digit sequence displayed on a screen, as quickly and as accurately as possible, using the left hand

Sponsors and collaborators

Lead sponsor

Friedhelm Hummel

Other

Registry information

Official study title

Non-invasive Brain Stimulation to Enhance the Effects of Training in Healthy Old and Patients With Focal Brain Lesions

Acronym: TrainStim

Important dates

Study start
2017
Primary completion
2025
Study completion
2025
First posted
Jul 10, 2025
Registry last updated
Jul 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.