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Completed

NCT Number: NCT05076773

TPVB, PECSB, ESPB for Postmastectmy Pain

Aim of the work The aim of the study is to compare between the effects of ultrasound guided thoracic paravertebral block, pectoral nerve block II, and erector spinae block in management of pain during cancer breast surgeries. The hypothesis of the study is that the three groups will give comparative results.

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Key information

Conditions

Pain, Postoperative Neurologic Manifestations Pain Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

18 year–60 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Medicine Menofia University

Shibīn al Kawm, Menofia, 32511, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ASA physical status classification class I or II
  • Age group 18 - 60 years of the female gender
  • Patients undergoing breast cancer surgeries

Exclusion criteria

  • Patient refusal
  • History of hypersensitivity to local anesthetics
  • Bleeding disorders or patients receiving anticoagulants
  • Spine or chest wall deformities
  • Pregnancy
  • Local infection at the site of injection.

Treatment and study plan

Ultrasound guided block

Procedure

Giving one regional block

Other names: Us guided paravertebral block, Us guided erector spinae block, Us guided PECs 1 and 2

IV morphine

Drug

given when VAS>3

Primary outcomes

  1. The primary outcome of the study will be duration of analgesia (time to first rescue analgesia after administration of the block).

    Time frame: 0-24o minutess

    minutes

Secondary outcomes

  1. Postoperative pain

    Time frame: 48 hours

    assessed by VAS score (0-10) where 0=no pain and 10=worst pain

  2. Total morphine consumption

    Time frame: 48 hours

    recorded postoperatively in mg

  3. Postoperative nausea and vomiting (PONV)

    Time frame: 48 hours

    4 points score of PONV (0-3) where 0=no PONV and 3=vomiting more than once

Sponsors and collaborators

Lead sponsor

Menoufia University

Other

Registry information

Official study title

A Comparative Study Between Ultrasound-guided Thoracic Paravertebral Block, Pectoral Nerves Block, and Erector Spinae Block for Pain Management in Cancer Breast Surgeries. A Randomized Controlled Study

Acronym: RCT

Important dates

Study start
2019
Primary completion
2021
Study completion
2021
First posted
Oct 13, 2021
Registry last updated
Oct 13, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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