Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07455942

Towards an Understanding of Barriers and Delays in the Diagnosis of Anal Cancer

This study examines care pathways in 300 patients with anal squamous cell carcinoma to identify barriers and delays in diagnosis, assess the impact of screening and access to care, and improve awareness, screening practices, and early diagnosis.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

This situational analysis will make it possible to identify barriers and delays in diagnosis, to assess waiting times for access to consultations, and to evaluate the existence of potential fast-track diagnostic pathways.

It will analyze the proportion of cancers diagnosed through screening as well as the proportion of eligible patients who did not benefit from screening.

Assessing patient reluctance, the impact of socio-economic conditions, and patients' knowledge of the link between HPV and anal cancer will help better target public information efforts.

Ultimately, the aim of the study is to improve care pathways in order to enhance public and healthcare professional awareness and promote earlier diagnosis.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male or female ≥ 18 years
  • Histologically proven invasive or microinvasive squamous cell carcinoma of the anus
  • Having read and understood the information letter provided, either:

i. After disclosure of the diagnosis, or ii. At the latest 6 months after initiation of treatment (surgical excision, radiotherapy, or chemoradiotherapy)

  • Affiliated with a social security system

Exclusion criteria

  • Refusal to participate in the protocol
  • Other histological types: lymphoma, adenocarcinoma, neuroendocrine tumor, etc.
  • Time since treatment initiation greater than 6 months
  • Protected persons (pregnant women, breastfeeding women, individuals under guardianship or curators, minors, persons deprived of liberty, or persons unable to express informed consent).

Treatment and study plan

Self-Administered Questionnaire

Other

Completion of a self-administered questionnaire by the patient to collect information about their care journey, any difficulties or hesitations, as well as their knowledge of the link between papillomavirus and cancer.

Primary outcomes

  1. First symptom(s) and the histological diagnosis

    Time frame: At the inclusion

    Time between the first symptom(s) and the histological diagnosis of anal squamous cell carcinoma.

Secondary outcomes

  1. Primary tumor, regional nodes, metastasis (TNM) ) stage comparison

    Time frame: At the inclusion

    Comparison of diagnostic stages and patient pathways according to whether or not they underwent scr

  2. Assessment of Deprivation and Health Inequalities for Health Examination Centers, French

    Time frame: At the inclusion

    French public-health index used to assess an individual's level of social and material deprivation based on living conditions, financial situation, social support, and access to healthcare. It helps identify social health inequalities and adapt medical care accordingly. [0 to 100], The higher the score → the greater the level of deprivation.

  3. Link between HPV and anal cancer

    Time frame: At the inclusion

    Proportion of patients aware of the link between HPV and anal cancer

  4. Performing a rectal examination at the first consultation

    Time frame: At the inclusion

    Assess the proportion of patients who underwent a clinical examination with rectal examination at the first consultation

Study contacts

Contact information is provided by the study sponsor or research team.

ISABELLE ETIENNEY

CONTACT

[email protected]

(0)1 44 64 20 16 51 ext. +33

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Intercommunal Creteil

Other

Registry information

Acronym: FRACAS

Important dates

Study start
2026
Primary completion
2028
Study completion
2028
First posted
Mar 6, 2026
Registry last updated
Jun 12, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.