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Completed

NCT Number: NCT03942133

Tow Techniques of Adductor Canal Block for Analgesia After Total Knee Replacement

This study compares the tow technique of continues adductor canal block for total knee replacement surgery. Half participants will receive catheterization at the entrance of the adductor canal, while the other half will receive catheterization at the middle point of the adductor canal.

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Key information

Conditions

Total Knee Arthroplasty Agnosia Analgesia Nerve Block Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pathological Conditions, Signs and Symptoms Perceptual Disorders Signs and Symptoms

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Peking Union Medical College Hospital

Beijing, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18-80 years
  • Knee-arthroscopy
  • Written consent
  • ASA I-III
  • BMI 19-35

Exclusion criteria

  • Unable to communicate with the investigators (e.g., a language barrier or a neuropsychiatric disorder).
  • coagulopathy or on anticoagulant medication
  • Allergic reactions toward drugs used in the trial
  • History of substance abuse
  • Infection at injection site
  • Can not be mobilised to 5 meters of walk pre-surgery

Treatment and study plan

ultrasound-guided short-axis placement of catheter at the entrance of the adductor canal

Procedure

Ultrasound probe is placed at the entrance of the adductor canal in short axis ，insertion of a PAJUNK Contiplex S catheter with the tip of the catheter located at the entrance of the canal

ultrasound-guided long-axis placement of catheter at the middle of the adductor canal

Procedure

Ultrasound probe is placed at the middle of the adductor canal in long axis with the caphelad end of the probe aligned with the entrance of the canal. insertion of a PAJUNK Contiplex S catheter with the tip of the catheter located at the middle of the canal

Primary outcomes

  1. cumulative sulfentanil consumption at 24 hours after surgery

    Time frame: 24 hours after surgery

Secondary outcomes

  1. the strength of quadriceps femoris

    Time frame: 0,2,4,8,24,48 hours postoperatively

    Quadriceps strength was assessed on a 0-5 scale as per the Medical Research Council Scale quadriceps motor strength(0 = no voluntary contraction possible, 1 = muscle flicker, but no movement of limb, 2 = active movement only with gravity eliminated, 3 = movement against gravity but without resistance, 4 = movement possible against some resistance and 5 = normal motor strength against resistance)

  2. The pain scores at rest determined by the numeric rating scale (NRS, 0-10)

    Time frame: at 0,2,4,8,24,48 hours postoperatively

    11-point numerical rating scale (NRS; 0, no pain; 10, maximum pain imaginable).

  3. The pain scores on adduction of the keen determined by the numeric rating scale (NRS, 0-10)

    Time frame: at 0,2,4,8,24,48 hours postoperatively

    11-point numerical rating scale (NRS; 0, no pain; 10, maximum pain imaginable).

  4. incidence of postoperative nausea and vomiting (PONV)

    Time frame: within 48 hours after surgery

  5. Patient satisfaction with anesthesia

    Time frame: within 5th day after surgery

    Patient satisfaction with anesthesia was assessed using a 5-point scale (5, very satisfied; 4, satisfied; 3, neither satisfied nor dissatisfied; 2, dissatisfied; 1, very dissatisfied)

  6. complications

    Time frame: within 3days after surgery

    Record complications including catheter dislodgment, puncture point infection, leakage,falling down,et al.

  7. cumulative sulfentanil consumption at other time points after surgery

    Time frame: 2,4,8,48 hours postoperatively

Sponsors and collaborators

Lead sponsor

Peking Union Medical College Hospital

Other

Registry information

Official study title

Ultrasound-guided Continuous Adductor Canal Block for Analgesia After Total Knee Replacement: Comparison of Block at the Entrance and Middle of the Canal

Important dates

Study start
2019
Primary completion
2019
Study completion
2019
First posted
May 8, 2019
Registry last updated
Jan 2, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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