Total Xenoestrogen Body Burden in Relation to Mammographic Density, a Marker of Breast Cancer Rlisk

Mammographic density is sensitive to estorgen exposure and constitutes a strong intermediate maker of breast cancer risk. We hypothesize that women with higher serum xenoestrogen levels will have greater mammographic density.

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Key information

Conditions

Breast Cancer Risk

Age range

55 year–70 year

Sex eligibility

Female

Study type

Observational

Primary location

University of Wisconsin Hospital

Madison, Wisconsin, 53792, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

55-70 years of age, Post menopausal

Exclusion criteria

If they have ever used hormone replacment therapy or have ever used Tamoxifen or Raloxifene, Diag. with breast cancer have had breast implants or have had a mastectomy/

Treatment and study plan

Primary outcomes

Characterize the distribution of total xenoestrogen burden and identify important source of xenoestrogen exposure among a clinic-based sample of postmenopausal women.

Time frame: 1 year

Secondary outcomes

Evaluate the association of total xenoestorgen exposure with mammographic density.

Time frame: 1 year

Sponsors and collaborators

Lead sponsor

University of Wisconsin, Madison

Other

Collaborators

United States Department of Defense

Registry information

Official study title

Total Xenoestrogen Body Burden in Relation to Mammographic Density, a Marker of Breast Cancer Risk

Important dates

Study start: 2008
Primary completion: 2009
Study completion: 2010
First posted: Feb 9, 2009
Registry last updated: Nov 19, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed