Total Motile Sperm Count and Pregnancy Rate From Intrauterine Insemination

Intrauterine insemination (IUI) is one of the most important infertility treatments. Infertility is failure to establish pregnancy (>12 months) with regularly unprotected sexual intercourse. Post-wash total motile sperm count (TMSC) vaguely defined as a predictor of IUI pregnancy rate. The minimum value required is also not clear. This study aimed to further define the relationship and determine the minimum recommended value to achieve a satisfactory IUI pregnancy rate.

Post-wash TMSC is predictive of IUI success. No optimal cut-off could be identified. In conclusion, post-wash TMSC is highly suggested as a quantitative predictor along with others in counseling and informed consent. The recommended threshold value is >3 x 106.

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Key information

Conditions

Insemination Genital Diseases Infertility Urogenital Diseases

Sex eligibility

Female

Study type

Observational

Primary location

Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran

Bandung, West Java, 40161, Indonesia

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

post-wash total motile sperm count needed to be over 5 x 10^5

Exclusion criteria

missing data on pregnancy outcome and missing medical records

Treatment and study plan

Intrauterine Insemination

Procedure

Transfer of sperm into the fallopian tube through a specialised cannula

Primary outcomes

Pregnancy rate

Time frame: max 9 months

Pregnancy number divided by number of IUI cycles

Sponsors and collaborators

Lead sponsor

Universitas Padjadjaran

Other

Registry information

Official study title

Effect of Post-Wash Total Motile Sperm Count on the Pregnancy Rate of Infertility Patients Undergoing Intrauterine Insemination

Important dates

Study start: 2022
Primary completion: 2022
Study completion: 2023
First posted: Aug 21, 2023
Registry last updated: Aug 21, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed