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Completed

NCT Number: NCT06578806

Tooth Loss Rate and Its Associated Factors: a Retrospective Cross-sectional Study With up to 50 Years of Follow-up.

This study will evaluate, in an adult population (n=448) previously diagnosed with gingivitis and/ or periodontitis, the tooth loss rate and its potential associated factors such as diabetes, smoking, bruxism, cardiovascular diseases, and also the effect of supportive periodontal therapy on these factors, with an up to 50 years of follow-up period.

Significant results of the present study will help in the future reduction of tooth loss among periodontally involved patients.

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Key information

Conditions

Tooth Loss Behavior Bruxism Cardiovascular Diseases Diabetes Mellitus Endocrine System Diseases Glucose Metabolism Disorders Habits Metabolic Diseases Mouth Diseases Nutritional and Metabolic Diseases Periodontal Diseases Periodontitis Smoking Stomatognathic Diseases Tooth Diseases

Age range

20 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age > 20 years.
  • Patients diagnosed with generalized chronic periodontitis or gingivitis.
  • At least 10 years of follow-up after 1st visit.
  • All treatments and recall sessions were done by the same operator at the same specialized dental clinic.

Exclusion criteria

  • Patients with healthy periodontal status.
  • Patients with orofacial anomalies and syndromes.
  • Patients receiving periodontal treatments by different operators.
  • Patients receiving periodontal treatments at different clinics.
  • Patients receiving bisphosphonate therapy.
  • Patients receiving chemotherapy or radiotherapy.
  • Patients receiving a hormonal therapy.
  • Patients with a history of refractory periodontitis or repeated abscess formation.
  • Patients with debilitating diseases that could impair the immune system (HIV/AIDS, cancer, or autoimmune diseases).

Treatment and study plan

Primary outcomes

  1. Tooth loss rate

    Time frame: From 10 up to 50 years

    Number of teeth lost (initial - final) / number of years of follow-up

Sponsors and collaborators

Lead sponsor

Saint-Joseph University

Other

Registry information

Official study title

Tooth Loss Rate and Its Associated Factors in Adult Population: a Retrospective Cross-sectional Study With up to 50 Years of Follow-up.

Important dates

Study start
1970
Primary completion
2020
Study completion
2024
First posted
Aug 29, 2024
Registry last updated
Aug 29, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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