Tavapadon
DrugOral tablets
Other names: CVL-751
NCT Number: NCT05404529
The primary purpose of the study is to assess the effect of hepatic impairment on the PK of tavapadon following administration of a single oral dose in participants with mild and moderate hepatic impairment relative to age, body weight, and sex-matched participants with normal hepatic function.
Looking for future studies?
Notify Me18 year–75 year
All sexes
Interventional
Phase 1
Miami, Florida, Miami, Florida, United States
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Key Inclusion Criteria:
Key Exclusion Criteria:
Note: Other protocol-defined Inclusion/Exclusion criteria may apply.
Oral tablets
Other names: CVL-751
Time frame: pre-dose and at multiple timepoints post-dose up to Day 7
Time frame: pre-dose and at multiple timepoints post-dose up to Day 7
Time frame: pre-dose and at multiple timepoints post-dose up to Day 7
Time frame: Day 1 up to Follow-up (Day 15)
Time frame: Day 1 up to Follow-up (Day 15)
Time frame: Day 1 up to Follow-up (Day 15)
Time frame: Day 1 up to Follow-up (Day 15)
Time frame: Day 1 up to Follow-up (Day 15)
Time frame: Day 1 up to Follow-up (Day 15)
Cerevel Therapeutics, LLC
Industry
A Phase 1 Open-label Trial to Evaluate the Pharmacokinetics and Safety Following Single Dose of Tavapadon in Participants With Mild and Moderate Hepatic Impairment Compared to Participants With Normal Hepatic Function
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06911320
Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications
Orlando, Florida, United States
View Trial DetailsNCT03289234
Healthy, Hepatic Impairment
Fukuoka, Japan
View Trial DetailsNCT04332432
Hepatic Impairment
Rialto, California, United States
View Trial DetailsNCT06736223
Hepatic Impairment
Sofia, Bulgaria
View Trial Details