To Evaluate the Effectiveness and Safety of the Single-port Robotic-assisted Breast Surgery in Breast Cancer

• Female patients, aged 18-75 years old; The pregnancy test (-) and reliable contraceptive methods are required for premenopausal and perimenopausal patients;
• Patients with the diagnosed breast cancer confirmed by core needle biopsy and unilateral operation was performed; Breast cancer patients with tumor node metastasis stage 0-III according to the 8th edition of the American Joint Commission on Cancer; Preoperative clinical examination or imaging evaluation shows that the distance between the tumor and the Nipple Areolar Complex (NAC) is more than 1cm. The tumor has a diameter of 2-3 cm and can be located in any quadrant or reduced to 3 cm through preoperative neoadjuvant chemotherapy. The distance between the lesion and the skin should be at least 8-10 mm;
• There is no clinical or imaging evidence to prove that the tumor has invaded the skin, chest wall, or nipple areola complex;
• There are indications for breast preservation, but the patient has a strong desire for reconstruction and is unwilling to undergo breast preservation surgery;
• Preventive mastectomy (BRCA1/2 malignant mutation with obvious family history of breast cancer and other high-risk groups);
• Preoperative clinical manifestations and imaging data showed no distant metastasis;
• No history of breast cancer or other serious underlying diseases in the past;
• Karnofsky performance status score ≥ 70;
• Eastern Cooperative Oncology Group score ≤ 2 ;
• The surgical procedure includes a single-port robot (intraperitoneal endoscopic surgical system) for total mastectomy with preservation of the nipple and areola, sentinel lymph node biopsy, axillary lymph node dissection, and stage I breast prosthesis implantation;
• Participants are able to understand the research process, voluntarily join the study, sign informed consent forms, have good compliance, and cooperate with follow-up;
• No swallowing difficulties; No shoulder joint movement disorders;
• Complete clinical data.

Exclusion criteria

• Male breast cancer or inflammatory breast cancer;
• Metastatic breast cancer (stage IV); Tumor invasion of the skin, pectoralis major muscle, or NAC;
• The clinical data is basically incomplete;
• Previously received chemotherapy in an external hospital or has undergone tumor resection in an external hospital;
• Bilateral breast cancer surgery;
• Other surgical methods;
• Preoperative distant metastasis or supraclavicular lymph node dissection;
• Complicated with other malignant tumors or had malignant tumors other than breast cancer in recent 5 years;
• The serious disease of non malignant tumors combined will affect the patient's compliance or put the patient in a dangerous state;
• Dementia, intellectual disability, or any mental illness that hinders understanding of informed consent forms.