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Active, Not Recruiting

NCT Number: NCT07037329

To Determine the Effectiveness of TENS vs EMS on Hemodynamics Parameters of Hypertension

This study aimed to evaluate the comparative effectiveness of Transcutaneous Electrical Nerve Stimulation (TENS) and Electrical Muscle Stimulation (EMS) on hemodynamic parameters in patients with hypertension. A total of 42 hypertensive patients were randomly divided into two equal groups: Group A received TENS, and Group B received EMS, over a period of four weeks. Pre- and post-treatment measurements of systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were recorded. Results showed that both TENS and EMS produced significant improvements in all parameters within their respective groups.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Age range

25 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Yasin Poly Clinic, Behria town Lahore

Lahore, Pakistan

About this study

However, the TENS group demonstrated a greater reduction in SBP and DBP, while the EMS group showed better improvement in heart rate control. The findings suggest that both treatments are effective non-pharmacological options for managing hypertension, with TENS being more effective overall in lowering blood pressure. These modalities may offer supportive benefits in long-term hypertension management strategies.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • (25-60 years) including both male and female
  • Patients clinically diagnosed with primary (essential) hypertension.
  • Blood pressure ranging from 140/90 mmHg to 160/100 mmHg (Stage 1 to early Stage 2 hypertension).
  • Participants who are not currently on intensive antihypertensive therapy or are on a stable dose of medication.
  • Willingness to participate voluntarily and provide written informed consent.
  • Patients who are not involved in any physical activity.
  • Participants who are overweight according to normal BMI.

Exclusion criteria

  • Secondary hypertension due to renal, endocrine, or other systemic causes. Individuals with pacemakers, implanted defibrillators, or other electronic medical devices.
  • Patients with severe cardiovascular conditions, such as recent myocardial infarction, heart failure, or arrhythmias.

History of seizure disorders or epilepsy. Cancer Patients

  • Presence of skin lesions, open wounds, or infections at the site of electrode placement.
  • Patients undergoing physiotherapy or electrical therapy elsewhere during the study period.
  • Individuals with known neurological or musculoskeletal disorders that could interfere with EMS or TENS effectiveness

Treatment and study plan

Transcutaneous Electrical Nerve Stimulation (TENS)

Diagnostic Test

TENS is a non-invasive electrotherapy technique used to manage pain and modulate physiological responses such as blood pressure. In this study, patients in Group 1 received TENS therapy as the primary intervention.

Electrical Muscle Stimulation (EMS)

Diagnostic Test

EMS is a form of electrotherapy that causes muscle contractions through electrical impulses delivered via surface electrodes. In this study, patients in Group 2 received EMS therapy to investigate its effect on hemodynamic parameters in individuals with hypertension.

Primary outcomes

  1. SF-36 Health Survey (Optional for Quality of Life)

    Time frame: 6 Month

    Measures general health status and quality of life 36 items grouped into 8 domains (e.g., physical functioning, general health)

    Each domain scored from 0 (worst) to 100 (best)

Sponsors and collaborators

Lead sponsor

Superior University

Other

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jun 25, 2025
Registry last updated
Jun 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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