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NCT Number: NCT06949787

To Compare Sweeping of Membranes Versus Expectant Management for Spontaneous Onset of Labor and Vaginal Delivery.

The study is planned to fill the gaps regarding the effectiveness of sweeping of membranes versus expectant management in terms of spontaneous onset of labor and vaginal delivery in post-date primigravida.

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Key information

Conditions

Post-Term Pregnancy Female Urogenital Diseases and Pregnancy Complications Pregnancy Complications Pregnancy, Prolonged Urogenital Diseases

Age range

18 year–40 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

About this study

This study is important as it provides localized data on the effectiveness and practicality of membrane sweeping in a low-resource setting, which is underrepresented in current literature. Potential benefits of this research may include reduced need for formal labor induction, lower healthcare costs, and improved maternal and neonatal outcomes. The findings may enhance clinical practices by offering an evidence-based, patient-friendly approach to managing postdate pregnancies, particularly in resource-limited settings where induction facilities are constrained.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Primigravid women
  • Aged between 18 and 40 years
  • Gestational age ≥40 weeks, confirmed by ultrasound or early dating scan
  • Singleton pregnancies
  • Cephalic presentation

Exclusion criteria

  • Multiple gestations
  • Fetal distress or anomalies detected on ultrasound
  • Contraindications to vaginal delivery (e.g., placenta previa, previous uterine surgery)
  • Previous uterine scar

Treatment and study plan

Membrane sweeping

Procedure

Participants in the membranes sweeping group will receive membrane sweeping. If labor will not initiate within 48 hours, the procedure will be repeated up to a maximum of three times at 48-hour intervals.

Primary outcomes

  1. Spontaneous onset of labor and vaginal delivery

    Time frame: 6 days

    The occurrence of regular uterine contractions (contractions occurring every 3-5 minutes, each lasting 30-60 seconds, and progressively increasing in intensity) leading to cervical changes without any form of labor induction will mark the achievement of spontaneous onset of labor.

Study contacts

Contact information is provided by the study sponsor or research team.

Aisha Ashraf

CONTACT

[email protected]

+923059501195

Tahir Riaz, FCPS

CONTACT

[email protected]

+923237426210

Sponsors and collaborators

Lead sponsor

Muhammad Aamir Latif

Other

Registry information

Official study title

Comparison of Spontaneous Onset of Labor and Vaginal Delivery in Post-date Primigravida Undergoing Sweeping of Membranes Versus Expectant Management

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Apr 29, 2025
Registry last updated
Apr 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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