TNF Polymorphism and Implantation Rate

Do TNF-308 and -238 polymorphisms impact the embryo implantation rate after in vitro fertilization (IVF) in women without female infertility factor ?

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Key information

Conditions

Infertility Genital Diseases Urogenital Diseases

Age range

18 year–37 year

Sex eligibility

Female

Study type

Observational

Primary location

Nice University Hospital

Nice, 06000, France

About this study

This study was performed in order to verify whether TNF-308 allele was associated with a higher implantation rate and multiple pregnancy rates in women without known infertility factors after ovarian hyperstimulation with exogenous FSH for IVF

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Women
normal karyotype,
age under 38 years
serum follicle-stimulating hormone (Day-3 FSH) levels below 10 UI/l

Exclusion criteria

age under 18 years

Treatment and study plan

biological and ultrasound test

Procedure

biological and ultrasound test 20 days after implantation in order to see the implantation rate

Primary outcomes

Implantation rate by biological test

Time frame: 20 days after implantation
Implantation rate by ultrasound test

Time frame: 20 days after implantation

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Nice

Other

Registry information

Official study title

Tumor Necrosis Factor-308 Polymorphism a Embryo Implantation Rate in Women Undergoing in Vitro Fertilization

Important dates

Study start: 2009
Primary completion: 2013
Study completion: 2013
First posted: Jun 21, 2016
Registry last updated: Jun 21, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed