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NCT Number: NCT07547943

TMH And Ultrasound For Difficult Airway Prediction

This prospective observational study aims to evaluate the predictive value of thyromental height (TMH) and ultrasonographic airway measurements in predicting difficult airway in adult patients undergoing elective surgery under general anesthesia.

Preoperative airway assessment will include standard clinical evaluation, TMH measurement, and ultrasonographic measurements of anterior neck soft tissue. Perioperative airway management data, including intubation difficulty, number of attempts, and Cormack-Lehane classification, will be recorded.

The relationship between preoperative measurements and difficult airway will be analyzed to determine their predictive accuracy and clinical usefulness.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Bursa City Hospital

Bursa, Nilüfer, 16110, Turkey (Türkiye)

About this study

Difficult airway management remains a critical issue in anesthetic practice, associated with significant morbidity and mortality. Traditional clinical airway assessment methods have limited sensitivity and specificity in predicting difficult airway. Recently, thyromental height (TMH) and ultrasonographic airway measurements have been proposed as promising tools for improving prediction accuracy.

This prospective, single-center observational study will be conducted in adult patients undergoing elective surgery under general anesthesia. Patients aged 18 years and older with ASA physical status I-III will be included.

Preoperative evaluation will include standard airway assessment methods such as Mallampati score, mouth opening, sternomental distance, and thyromental distance. In addition, TMH will be measured, and ultrasonographic measurements of anterior neck soft tissues will be performed, including skin-to-epiglottis distance, pretracheal soft tissue thickness, and hyomental distance.

Perioperative airway management data will be recorded, including Cormack-Lehane classification, number of intubation attempts, use of adjunct airway devices, and intubation difficulty score.

The primary objective is to evaluate the predictive value of TMH and ultrasonographic measurements for difficult airway. Secondary objectives include assessing their relationship with intubation difficulty, number of attempts, and airway-related complications.

The findings of this study are expected to contribute to improved preoperative airway assessment and safer airway management strategies in clinical practice.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adult patients aged 18 years and older Patients scheduled for elective surgery under general anesthesia Patients requiring endotracheal intubation Patients who provide written informed consent

Exclusion criteria

  • Patients with known upper airway pathology (e.g., tumor, trauma, infection) Patients with previous head and neck surgery or anatomical deformity affecting airway evaluation Patients with limited mouth opening (<3 cm) or severe cervical spine restriction Patients with contraindications to ultrasonographic examination Patients requiring rapid sequence induction or emergency surgery Patients who refuse to participate

Treatment and study plan

Primary outcomes

  1. Prediction of Difficult Intubation

    Time frame: During induction of anesthesia (intraoperative period)

    The primary outcome is the ability of thyromental height (TMH) and ultrasonographic airway measurements to predict difficult intubation. Difficult intubation will be defined as Cormack-Lehane grade ≥3, requirement of multiple intubation attempts, or use of advanced airway devices.

Study contacts

Contact information is provided by the study sponsor or research team.

Serra Topal, MD

CONTACT

[email protected]

05068823855

Sponsors and collaborators

Lead sponsor

Bursa City Hospital

Other Gov

Collaborators

  • Ulusoy, Emre, M.D.

Registry information

Official study title

Comparative Evaluation Of Thyromental Height And Ultrasonographic Airway Measurements In Predicting Difficult Airway: A Prospective Observational Study

Acronym: TMH-USG

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Apr 23, 2026
Registry last updated
Apr 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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