Skip to main content
OpenTrials
Completed

NCT Number: NCT05258955

Title: Comparison of Anti-plaque Efficacy of Natural Honey With Chlorhexidine Mouthwash: A Randomized Controlled Trial

The rationale of our study is to compare the efficacy of natural honey base preparation with other commercially available mouthwashes i.e chlorhexidine base in prevention of dental plaque formation as honey is readily available and cost effective and organic in nature. This study will help to provide the data of our community and positive result may provide a new method of oral hygiene maintenance with fewer side effects. We will be able to deliver the best anti-plaque agent.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Dental Plaque Dental Deposits Stomatognathic Diseases Tooth Diseases

Age range

18 year–25 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

Liaquat College of Medicine and Dentistry

Karachi, Sindh, 75800, Pakistan

About this study

In this study, participants will assigned into 2 group those who will fulfilled the inclusion and exclusion criteria. After the informed consent, they were divided into 2 group. Group A will received Chlorhexidine mouthwash and Group B will provided with honey based mouthwash. The participant will blinded as solution will be provided in dark color bottle to mask the study. After which the baseline plaque index will be taken followed by recording plaque index on 7th, 14th, and 21st day. The statistical analysis will be done to compare the mean difference between these 2 groups

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Individual aged between 18-25
  • Retained 28 number of teeth excluding wisdom teeth

Exclusion criteria

  • Individual with medical illness affecting oral cavity like diabetes, sjögren syndrome, crohn disease etc
  • Multiple extraction , overhang restoration, wearing any appliance
  • Periodontal problem with pocket depth more than 3mm
  • Current or recent history of antibiotic consumption
  • Noncompliance that is unable to maintain their hygiene.
  • Pan, Betel quid and any other oral habit will not be included in study

Treatment and study plan

Natural honey

Other

Natural Sidr honey based mouthwash used as intervention group B (Arm Group B) for the reduction of plaque index

Other names: Sidr Honey

Chlorhexidine mouthwash

Drug

Chlorhexidine gluconate 0.12% mouthwash is used as intervention in Group A (Arm Group A) for the comparison of plaque reduction among group A and B

Other names: Chlorhexidine Gluconate

Primary outcomes

  1. Dental Plaque

    Time frame: reduction of plaque index will be assessed on 7th day, 14th day and on 21st day

    primary outcome is to assessed the reduction on plaque level among Group A and Group B

Sponsors and collaborators

Lead sponsor

Liaquat National Hospital & Medical College

Other

Collaborators

  • Liaquat College of Medicine and Dentistry

Registry information

Official study title

Comparison of Anti-plaque Efficacy of Natural Honey With Chlorhexidine Mouthwash: A Randomized Controlled Trial

Important dates

Study start
2020
Primary completion
2020
Study completion
2021
First posted
Feb 28, 2022
Registry last updated
Feb 28, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.