Tiotropium Respimat Administration With and Without Aerochamber Disease (COPD)

• COPD patient who is on Tiotropium Respimart and other inhalers continued.
• Those fullfill inclusion criteria will be randomized into two group.
• To do Baseline CAT score and SGRQ questionnaires with Lung function test.
• Assess inhaler technique with and without aerochamber.
• Teach proper inhaler technique by templates and demonstrate to patients.
• Group A given aerochamber and Group B without aerochamber enroll in the study for total 18 week .
• First phase for 8 week after that 2 week of washout periode (without aerochamber both arm).
• Then Group A without aerochamber and Group B with aerochamber continue with all inhalers for 8 week.
• Followed up at 8th , 11th and 18th week to assess inhaler techniques ,Lung function test and do CAT score, and SGRQ questionnaire.
• Analysis data

Inclusion criteria

• COPD patients under Respiratory clinic UKM follow up

• Patients who are with stable COPD (no exacerbation past 2 months)
• Age same and more than 40-year-old
• Patient able to perform inhaler medication
• Patient able to perform technically acceptable pulmonary function test

Exclusion criteria

• Drug hypersensitivity
• Bronchial Asthma
• Significant disease that may influence patient's ability to participate in the study.
• Unable to provide signed informed consent
• Mental condition rendering the subject unable to understand the nature, scope and the possible consequences of the study.