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Completed

NCT Number: NCT03404271

Time-Restricted Feeding Plus Resistance Training in Active Females

The objective of this study is to examine the effects of time-restricted feeding (TRF; consuming all calories within an 8-hour period of time each day) and resistance training, with or without the addition of the dietary supplement HMB, on body composition, muscular performance and physiological outcomes in active females.

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Key information

Conditions

Healthy Active Females

Age range

18 year–30 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Texas Tech University

Lubbock, Texas, 79409, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Female between 18 and 30 years of age
  • Current university affiliation
  • Weighing at least 110 pounds
  • Generally healthy
  • Resistance-trained
  • Schedule availability to complete supervised resistance training
  • Body fat percentage between 15 and 29%

Exclusion criteria

  • Pregnant or trying to become pregnant
  • Currently breastfeeding
  • Any disease, condition or orthopedic limitation that would prevent safe participation in resistance training or time-restricted feeding
  • Current smoker
  • Presence of pacemaker or other electrical implant
  • Allergic to dairy proteins

Treatment and study plan

Beta-hydroxy beta-methylbutyrate

Dietary Supplement

3 grams per day of the calcium salt form of beta-hydroxy beta-methylbutyrate (HMB).

Other names: HMB

Resistance training

Other

Performing supervised resistance training three times per week.

Protein supplementation

Dietary Supplement

Consuming a protein supplement daily.

Time-restricted feeding

Behavioral

Consuming all calories within a specified 8-hour period of time each day.

Other names: Intermittent Fasting

Primary outcomes

  1. Fat mass

    Time frame: 8 weeks

    Assessed using multi-compartment model

  2. Fat-free mass

    Time frame: 8 weeks

    Assessed using multi-compartment model

  3. Body fat percentage

    Time frame: 8 weeks

    Assessed using multi-compartment model

  4. Upper body muscle hypertrophy

    Time frame: 8 weeks

    Muscle thickness of elbow flexor muscles

  5. Lower body muscle hypertrophy

    Time frame: 8 weeks

    Muscle thickness of knee extensor muscles

Secondary outcomes

  1. Lower body muscular strength

    Time frame: 8 weeks

    Assessed by 1RM on leg press

  2. Lower body muscular power characteristics

    Time frame: 8 weeks

    Assessed during vertical jump and isometric squats

  3. Lower body muscular endurance

    Time frame: 8 weeks

    Assessed by repetitions to failure on leg press

  4. Upper body muscular strength

    Time frame: 8 weeks

    Assessed by 1RM on bench press

  5. Upper body muscular endurance

    Time frame: 8 weeks

    Assessed by repetitions to failure on bench press

  6. Cortisol awakening response

    Time frame: 8 weeks

    Assessed via analysis of saliva samples

  7. Lipid panel

    Time frame: 8 weeks

    Measured from fasted blood sample

  8. Blood glucose

    Time frame: 8 weeks

    Measured from fasted blood sample

  9. Blood insulin

    Time frame: 8 weeks

    Measured from fasted blood sample

  10. Blood C-reactive protein

    Time frame: 8 weeks

    Measured from fasted blood sample

  11. Blood pressure

    Time frame: 8 weeks

    Measured using automated device

  12. Arterial compliance

    Time frame: 8 weeks

    Assessed by applanation tonometry

  13. Resting metabolic rate

    Time frame: 8 weeks

    Assessed by indirect calorimetry

  14. Respiratory quotient

    Time frame: 8 weeks

    Assessed by indirect calorimetry

  15. Mood

    Time frame: 8 weeks

    Assessed by questionnaire

  16. Eating behavior

    Time frame: 8 weeks

    Assessed by three-factor eating questionnaire R18

  17. Sleep quality

    Time frame: 8 weeks

    Assessed by Pittsburgh Sleep Quality Index

  18. Physical activity level

    Time frame: 8 weeks

    Assessed by accelerometry.

Sponsors and collaborators

Lead sponsor

Texas Tech University

Other

Collaborators

  • Dymatize Enterprises, LLC
  • Metabolic Technologies Inc.

Registry information

Official study title

Time-Restricted Feeding Plus Resistance Training in Active Females: Effects on Body Composition, Muscular Performance and Physiological Variables

Important dates

Study start
2018
Primary completion
2018
Study completion
2018
First posted
Jan 19, 2018
Registry last updated
Sep 12, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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