Thyroid Hormone Values and Anti-thyroid Peroxidase Antibody Positivity in Recurrent Pregnancy Loss

The aim of this study is to compare the thyroid hormone values and anti-thyroid peroxidase (anti-TPO) levels of women with a diagnosis of recurrent pregnancy loss (RPL) and healthy pregnancies. The primary objective is to find out the relationship between recurrent pregnancy loss with thyroid hormone levels and anti-TPO positivity.

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Key information

Conditions

Autoimmune Thyroiditis Abortion, Habitual Abortion, Spontaneous Autoimmune Diseases Endocrine System Diseases Female Urogenital Diseases and Pregnancy Complications Immune System Diseases Pregnancy Complications Recurrent Miscarriage Thyroid Diseases Thyroiditis Thyroiditis, Autoimmune Urogenital Diseases

Age range

18 year–45 year

Sex eligibility

Female

Study type

Observational

Primary location

Zonguldak Bulent Ecevit University Faculty of Medicine

Zonguldak, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

women with 2 or more pregnancy loses
for controls women with least one healthy baby

Exclusion criteria

any other metabolic disease
women with one miscarriage

Treatment and study plan

Primary outcomes

Anti-thyroid Peroxidase Antibodies

Time frame: 4 years

presence of Anti-thyroid Peroxidase Antibodies in both groups
Thyroid Hormone Levels

Time frame: 4 years

levels of Thyroid stimulant Hormone, Thyroxin and triiodothyronine levels

Sponsors and collaborators

Lead sponsor

Zonguldak Bulent Ecevit University

Other

Registry information

Official study title

Relationship Between Habitual Abortion With Thyroid Hormone Values and Anti-TPO (Anti-thyroid Peroxidase Antibody) Positivity

Important dates

Study start: 2018
Primary completion: 2022
Study completion: 2022
First posted: Jan 11, 2023
Registry last updated: Jan 11, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed