School of Dental Medicine, University at Buffalo
Buffalo, New York, 14214, United States
NCT Number: NCT03369405
Currently, the investigators are unaware of any previous studies that have analyzed the relationship between the prevalence of thyroid disease and chronic periodontitis among adults utilizing a retrospective, cross-sectional design. This study will review approximately 2000 patient records and compare the prevalence of thyroid disease in three groups with increasing severity of chronic periodontitis.
Looking for future studies?
Notify Me35 year and older
All sexes
Observational
Buffalo, New York, 14214, United States
This is a retrospective, cross-sectional patient records review study. Only records with subjects that were 35 years or older and have been active patients of the School of Dental Medicine, University at Buffalo will be included. Three individual searches with three distinct patient criteria will be conducted to obtain records from subjects in three populations with different degrees of periodontal disease. All subjects that qualify the eligibility criteria will be selected. The IT Department has access to select the subjects according to the eligibility criteria without requiring access to the physical patient record. The three subject groups are:
All duplicates within a group will be excluded (e.g. patients may have had a D1110 code more than once per year). These 3 subject search criteria should yield a sufficient number of patient records for statistical analysis.
All patient records will be reviewed and data will be collected and recorded in an electronic Microsoft Excel database file that is saved on an encrypted flash drive. The only patient identifier recorded will be the patient records number. Once data collection is complete, or at a maximum of 3 years from the start of the study, all identifying information will be deleted and only de-identified data saved on a separate electronic file will be analyzed. No code key will be required.
Data will be analyzed using ANOVA (F-test). If multiple variables are used, analysis will be by using generalized estimating equations (GEE).
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Duplicates within groups are eliminated.
Exclusion criteria
Note: the majority of patient records selected by the search criteria done electronically by the IT department will be included in the study, since the search criteria very closely overlaps the overall study criteria
There is no intervention - the three study groups are created by utilizing three unique sets of search criteria for the patient records review.
Time frame: Assessed at one time point only, during patient's initial exam noted in patient records (cross-sectional study).
The presence or absence of thyroid medication in the patient record will be used as a surrogate marker for thyroid disease presence or absence.
Time frame: Assessed at one time point only, during patient's initial exam noted in patient records (cross-sectional study).
Smoking history will be determined from the Medical Questionnaire form in the patient records.
Time frame: Assessed at one time point only, during patient's initial exam noted in patient records (cross-sectional study).
The Medical Questionnaire and the Medication List in the patient records will be referenced to determine the presence of diabetes.
Time frame: Assessed at one time point only, during patient's initial exam noted in patient records (cross-sectional study).
Number of teeth that have one or more sites that contain a 5mm or greater pocket, recorded in periodontal chart
Time frame: Assessed at one time point only, during patient's initial exam noted in patient records (cross-sectional study).
Number of teeth that have one or more sites that contain a 6mm or greater pocket, recorded in periodontal chart
Time frame: Assessed at one time point only, during patient's initial exam noted in patient records (cross-sectional study).
Total number of teeth, recorded in periodontal chart
Time frame: Assessed at one time point only, during patient's initial exam noted in patient records (cross-sectional study).
The Medication List in the patient records will be referenced to determine any history of proton pump inhibitor use.
Time frame: Assessed at one time point only, during patient's initial exam noted in patient records (cross-sectional study).
Percentage of tooth surfaces positive for plaque out of total tooth surfaces
Time frame: Assessed at one time point only, during patient's initial exam noted in patient records (cross-sectional study).
The presence or absence of hormone supplementation (birth control or hormone replacement therapy included)
Time frame: Assessed at one time point only, during patient's initial exam noted in patient records (cross-sectional study).
The Medication List in the patient records will be referenced to determine any history of bisphosphonate use.
University at Buffalo
Other
Thyroid Insufficiency as a Modifying Factor for Chronic Periodontitis
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06408909
Behavior, Endocrine System Diseases
Istanbul, Turkey (Türkiye)
View Trial DetailsNCT06036576
Abortion, Habitual, Abortion, Spontaneous
Baghdad, Iraq
View Trial DetailsNCT06383481
Endocrine System Diseases, Healthy Lifestyle
Erzurum, palandöken, Turkey (Türkiye)
View Trial DetailsNCT07681557
Endocrine System Diseases, Postoperative Voice Change
Ankara, Turkey (Türkiye)
View Trial Details