Anesthesiology and Critical Care Medicine, Edouard Herriot Hospital, Hospices Civils de Lyon
Lyon, 69003, France
NCT Number: NCT02385006
Type of study:Prospective, single-center, non-therapeutic, of routine care No randomization, no modifications of the usual care, study results are not available for the physicians in charge of the patient.
Objectives:
* The main objective of this study is to evaluate the ability of the thromboelastogram (ROTEM®) to detect clotting disorders related to pancreas-kidney transplantation, comparing ROTEM ® profiles during the perioperative period of two different types of transplantation (kidney alone and simultaneous pancreas-kidney) * The secondary objectives are:
1. To assess the incidence and type of coagulation disorders during the perioperative period of these two types of transplantation 2. To study correlation values between thrombolelastogram and standard coagulation parameters
Population study:
* Evaluated group: 40 pancreas-kidney recipients * Control group: 80 kidney recipients * Recruitment periods: 24 months * Patient Monitoring: 48 hours * Total duration of the study: 36 months. * Ethics: Study of routine care. Oral and written information given to patients. Validation of the study protocol by the local ethics committee (CPP Sud Est II: Protocol No. HCL / P 2012.727)
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Notify Me18 year and older
All sexes
Interventional
Not applicable
Lyon, 69003, France
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
-Enrollment in an other research protocol, incompatible with the trial according to the investigator
Time frame: preoperative period
Time frame: 45 min after transplant unclamp
Time frame: Intensice Care Unit admission
Time frame: 24 hours
Time frame: 48 hours
Time frame: preoperative period
Time frame: 45 min after transplant unclamp
Time frame: Intensice Care Unit admission
Time frame: 24 hours
Time frame: 48 hours
Hospices Civils de Lyon
Other
Thromboelastographic Profile During Simultaneous Pancreas-kidney Transplantation
Acronym: TEG-PKT
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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