ThRombectomy In Mild Ischemic Stroke With a Visible Intracranial veSsel Occlusion

Inclusion criteria

• Acute ischemic stroke in an adult patient (18 years of age or older).
• Onset (Last Seen Normal) time to treatment time <24 hours or unknown Last Seen Normal in whom Endovascular Therapy could be considered per local radiographic guidelines.
• Mild stroke defined as an NIH Stroke Scale ≤ 5 at the time of treatment decision.

a. Patients with NIH Stroke Scale=0 can be included in the study if they have relevant abnormalities on neurological exam.

• An acute intracranial vessel occlusion (Intracranial Internal Carotid Artery terminus (T or L clot), Middle Cerebral Artery (M1, M2, M3/beyond), Anterior Cerebral Artery (A1, A2, A3), V4, Basilar, Posterior Cerebral Artery) defined by non-invasive acute imaging (Computed Tomography, angiography (Computed Tomography Angiography) or Magnetic Resonance angiography (MRA)) that is neurologically relevant to the presenting symptoms and signs.

Exclusion criteria

• Stroke symptoms due to another non-ischemic acute neurological condition such as seizure with Post-ictal Todd's paralysis or focal neurological signs due to severe hypo- or hyperglycemia.
• Hyperdensity on Non-contrast Computed Tomography consistent with intracranial hemorrhage. Any clinical suspicion of any intracranial hemorrhage even in the absence of visible blood on baseline brain imaging.
• Large acute stroke >1/3 Middle Cerebral Artery territory or Alberta Stroke Programme Early CT score (ASPECTS<6 or established frank hypodensity relevant to the presenting acute stroke already visible on baseline CT scan.
• Findings on acute CT or MRI to suggest that the
• Patient has a severe or fatal or disabling illness that will impact decision regarding acute reperfusion therapies.
• Pregnancy.
• Clinical history, past imaging and clinical judgment suggest that the intracranial occlusion is chronic.
• Stroke occurred as an inpatient.
• Inclusion into any randomized control trials.