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Completed

NCT Number: NCT02689297

Three Different Oral Hygiene Regimes on Three Volatile Sulfur Compounds

The purpose of the study is to evaluate the effect of various oral hygiene regimes on three volatile sulfur compounds.

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Key information

Conditions

Halitosis Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Digestive

Age range

18 year–30 year

Sex eligibility

Male

Study type

Interventional

Phase

Phase 4

About this study

Thirty male monk volunteers who matched with the including criteria were divided randomly into two groups. Both groups were practiced to brush their teeth with scrubbing method for one week. Then, each group were instructed to do different additional protocol regimen- group A have to do mouth washing and tooth brushing and group B have to practice tongue cleaning addition to tooth brushing for three weeks. At the fifth week, both groups were instructed to practice tooth brushing, mouth washing and tongue cleaning. Three different volatile sulfur compounds were measured by oral chroma. Tongue characteristics, oral examination were checked as the outcomes of this study.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Clinical diagnosis of oral malodor
  • No systemic diseases and no severe dental diseases
  • At least 20 functional teeth

Exclusion criteria

  • Risky oral habit (smoking and betel quid chewing)
  • Current use of antibiotics or any drugs
  • Current use of any kind of mouthwash

Treatment and study plan

chlorine dioxide

Other

First week, subjects were instructed to do regular tooth brushing. After that group A was requested to use chlorine dioxide mouthwash two time per days for three weeks in addition to tooth brushing and then, one week for combination of tooth brushing, tongue cleaning and mouth washing.

small toothbrush for tongue cleaning

Other

First week, subjects were instructed to do regular tooth brushing. After that group B was requested to brush their tongue with small toothbrush two time per days for three weeks in addition to tooth brushing and then, one week for combination of tooth brushing, tongue cleaning and mouth washing.

Primary outcomes

  1. Three different volatile sulfur compounds

    Time frame: up to 5weeks

    Investigator measured three different volatile sulfur compounds: hydrogen sulfide, methyl mercaptan, dimethyl sulfide concentrations (ng/10ml) by using Oral chroma.

Secondary outcomes

  1. Oral Health examination

    Time frame: up to 5weeks

    As oral examination, investigator examined present teeth, DMF-T (decayed, missing and filled teeth)

  2. Tongue coating characteristics

    Time frame: up to 5weeks

    As tongue coating characteristics, investigator examined tongue coating score (by using winkle tongue coating index) at the baseline, one week later, four weeks later and five weeks later.

  3. Number of teeth with bleeding on probing

    Time frame: up to 5weeks

  4. Plaque index score

    Time frame: up to 5weeks

Sponsors and collaborators

Lead sponsor

Tokyo Medical and Dental University

Other

Registry information

Important dates

Study start
2013
Primary completion
2013
Study completion
2013
First posted
Feb 23, 2016
Registry last updated
Feb 23, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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