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OpenTrials
Completed

NCT Number: NCT01521858

THRA_hematologic Variables

Total hip replacement arthroplasty is a surgery having intra- and postoperative substantial blood loss. The investigators will investigate the relationship between the various hematologic variables and postoperative bleeding volume.

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Key information

Conditions

Avascular Necrosis of Hip

Age range

20 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Seoul National University Bundang Hospital

Seongnam, Gyounggi, 463-707, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • avascular necrosis of hip
  • total hip replacement arthroplasty

Exclusion criteria

  • revision operation
  • hematologic disease
  • anticoagulant medication
  • preoperative hemoglobin < 10 g/dl
  • preoperative transfusion of red blood cells

Treatment and study plan

Primary outcomes

  1. postoperative bleeding volume

    Time frame: at first postoperative day

  2. Hemoglobin

    Time frame: preoperative 1 day and postoperative 1 day

  3. hematocrit

    Time frame: preoperative 1 day and postoperative 1 day

  4. platelet

    Time frame: preoperative 1 day and postoperative 1 day

  5. prothrombin time_international normalized ratio

    Time frame: preoperative 1 day and postoperative 1 day

  6. activated partial prothrombin time

    Time frame: preoperative 1 day and postoperative 1 day

  7. fibrinogen concentration

    Time frame: preoperative 1 day and postoperative 1 day

  8. Rotational thromboelastometry

    Time frame: preoperative 1 day and postoperative 1 day

Secondary outcomes

  1. volume of infused fluid during operation

    Time frame: Period from starting to finishing the operation (During operaiton, an expected average of 3 hours)

    Infused total crystalloid and colloid volume during the operation will be recorded.

  2. intraoperative urine output

    Time frame: Period from starting to finishing the operation (During operaiton, an expected average of 3 hours)

  3. transfusion units

    Time frame: Period from starting to finishing the operation (During operaiton, an expected average of 3 hours) and postoperative first day

    Red blood cell

Sponsors and collaborators

Lead sponsor

Seoul National University Bundang Hospital

Other

Registry information

Official study title

Relations Between Hematologic Variables and Postoperative Bleeding in Total Hip Replacement Arthroplasty

Important dates

Study start
2012
Primary completion
2013
Study completion
2013
First posted
Jan 31, 2012
Registry last updated
Aug 29, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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