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Completed

NCT Number: NCT06744946

Thoracoscopic Talc Pleurodesis Versus Bleomycin -Tranxemic Acid Mixture Injection in Chest Tube in Malignant Pleural Effusion

Comparing Two Methods to Treat Fluid Build-up in Chest for Cancer Patients:Talc Powder Surgery versus Chest Tube Medicine.

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Key information

Conditions

Malignant Pleural Effusions (Mpe)- Pleurodesis Neoplasms Neoplasms by Site Pleural Diseases Pleural Effusion Pleural Effusion, Malignant Pleural Neoplasms Pleurodesis Respiratory Tract Diseases Respiratory Tract Neoplasms Thoracic Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Chest Department -Faculty of Medicine

Alexandria, Azarita, 11521, Egypt

About this study

Closure of the space where the effusion is recurrently accumulated through talc poudrage in thoracoscopy or bleomycin - tranxemic acid solution injection in chest tube.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 1. Adult patients (more than 18 years) with malignant pleural effusion or highly suspected exudate.
  • Fit patients for the procedure selected.

Exclusion criteria

  • Inability to provide informed consent for the procedure.
  • Hemodynamically unstable patients.
  • Bleeding diathesis.
  • Uncontrolled cough.
  • Hypoxic index less than 300.
  • Endobronchial obstruction.
  • Pleural thickening with trapped lung.

Treatment and study plan

thoracoscope

Procedure

bleomycin- tranxemic acid mixture pleurodesis versus thoracoscopic talc poudrage

Other names: intercostal tube

Primary outcomes

  1. Dyspnea Borg Scale

    Time frame: one month

    the rate of shortness of breath from number 0 to number 10

Sponsors and collaborators

Lead sponsor

Mohamed Sabry

Other

Collaborators

  • Alexandria University

Registry information

Official study title

Comparison Between Pleurodesis by a Combination of Bleomycin and Tranxemic Acid Solution and Thoracoscopic Talc Poudrage in Malignant Pleural Effusion

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Dec 20, 2024
Registry last updated
Dec 20, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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