Thoracic Ultrasound on Upper Gastrointestinal Bleeding (ECOBLEDSTUDY)

Inclusion criteria

• Patients with a diagnosis of UGIB documented by endoscopy.
• Any gender.
• Over 18 years old.

Exclusion criteria

• Patients with UGIB previously treated in other hospitals.
• Patients under 18 years of age.
• Patients with suspected UGIB who did not undergo endoscopy.
• Pregnant.
• Patients with chronic obstructive pulmonary disease.
• Patients with interstitial lung disease.
• Patients with pleural effusion at the time of admission to the emergency room.
• Refusal to participate in the protocol.

Method The investigators will study all patients who come to the emergency room of the hospital due to suspicion of UGIB (melena, hematemesis, vomiting in coffee grounds and hematochezia with hemodynamic instability). These patients will undergo a pulmonary and vena cava ultrasound.

Patients with suspected UGIB who are candidates for upper endoscopy during their hospital stay will undergo a second pulmonary and vena cava ultrasound ten minutes prior to upper endoscopy.

The investigators will include in the research study patients with UGIB documented by upper endoscopy. The investigators will perform a third pulmonary and vena cava ultrasound 24 hours after the endoscopic procedure.

The investigators will exclude patients with suspected UGIB but who are not candidates for endoscopy.

The technique used is a bilateral intercostal thoracic point-of-care ultrasound (TPOCUS) with the patient in supine decubitus with the head at 30 degrees. Each hemithorax will be divided into 4 areas: anterior and lateral, superior and inferior. The anterior area will be delineated between the clavicle and the diaphragm and between the parasternal line to the anterior axillary line. The lateral area will be delineated between the axilla and the diaphragm and between the anterior to the posterior axillary line. The superior area will be delineated from the 1st to the 3rd intercostal space and the lower area from the 4th to the 6th intercostal space. A total of 8 areas of the chest will be visualized during normal breathing.

The TPOCUS findings to report are:

B-type lines: Those lines are hydro-aerial artifacts presenting as comet tail images, begin in the pleural line, are hyper-echoic, well defined, disseminated towards the end of the screen, delete A-type lines, and move with the pleural slip when this it is present. The lines separated from each other around 7 mm correspond to interstitial edema, while those that distance 3 mm indicate the presence of alveolar edema. The presence of more than 3 B-type lines indicates the presence of an alveolar-interstitial syndrome.

The inferior cava vein evaluation will be performed by measuring the diameter and percentage of collapse of this vein. It will be performed in the subxiphoid window with the identification of the four cardiac chambers, then a 90º turn of the transducer will made in the cephalad direction, which will show the right atrium, the union of the inferior vena cava and the liver above it. The diameter measurement will be beyond the point of confluence of the hepatic veins, usually found approximately 2 cm from the union of the inferior vena cava and the right atrium. Based on the diameter and collapse percentage measurement of the inferior vena cava on spontaneous breathing, a volume status will be defined as lack of volume if the diameter is <2 cm and the collapse percentage is >50%; however, a diameter >2 cm and a collapse percentage <50% will be classified as hypervolemic state.

Inclusion criteria

• Age, more than 17 years old.
• Patients diagnosed with UGIB.
• Any etiology of the UGIB.

Exclusion criteria

• Patients with UGIB previously treated in other hospitals.
• Patients with UGIB with Blatchford scale less than 2 points.
• Pregnant women.
• Refusal to participate in the protocol.