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OpenTrials
Enrolling by Invitation

NCT Number: NCT07204665

This Study Has Been Designed to Support the Working Hypothesis That Emergency Surgery in a Colon Obstruction Neoplasm is Better Than Stent Bridge Due to Better Oncological Outcomes, Analyzing the Importance of ERAS Programs in Emergency Colon Obstruction Surgery.

This study has been designed to support the working hypothesis that emergency surgery in a colon obstruction neoplasm is better than stent bridge due to better oncological outcomes. The primary objective is to analyse the importance of ERAS program implementation in emergency colon obstruction surgery

Enrolling by Invitation

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Key information

Conditions

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Hospital de Urduliz

Bilbao, Vizcaya, 49600, Spain

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All adult patients (aged >18 years) with a diagnosis of Malignant obstruction colorectal cancer. Informed consent will be obtained from all subjects who will participate in the study voluntarily.
  • ASA I, II and III
  • No more than 5 days from symptoms onset.
  • Absence of proximal colon severe dilatation( no more than 8 centimeters), severe malnutrition.
  • No Inmunocompromised patients
  • Patients suffer from segmentary colectomy, with or without anastomosis with o witjhout lateral ileostomy
  • Patients suffer from Hartmann procedure.

Exclusion criteria

  • Patient refusal.
  • Patients under 18 years of age.
  • ASA IV
  • Stent placement
  • ICU stay more than 2 days
  • Peritonitis
  • Out of protocol if patient would need total parenteral nutrition(NPT) during postoperative or Clavien-Dindo more or equal than II.

Treatment and study plan

Primary outcomes

  1. Postoperative complications

    Time frame: From enrollment to 90 days

    The primary objective is to analyse the importance of ERAS program implementation in emergency colon obstruction surgery

Secondary outcomes

  1. 1 year survival analysis

    Time frame: 360 days after surgery

    1 year survival analysis

  2. Overall survival

    Time frame: 365 days after surgery

    Overall survival

  3. disease-related survival

    Time frame: 365 days after surgery

    disease-related survival

  4. disease-free survival

    Time frame: 365 days after surgery

    disease-free survival

  5. Relationship between stent bridge and colon perforation

    Time frame: 60 days after stent placement

    Relationship between stent bridge and colon perforation

Sponsors and collaborators

Lead sponsor

Universidad de Zaragoza

Other

Registry information

Official study title

European Study in Colon Obstruction

Acronym: EUCOBS

Important dates

Study start
2025
Primary completion
2026
Study completion
2027
First posted
Oct 2, 2025
Registry last updated
Oct 2, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.