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Completed

NCT Number: NCT04655859

Thiol/Disulfide and Oxidative Stress

The aim of this study was to evaluate the role of thiol/disulfide homeostasis and oxidative stress in the saliva of children with severe early childhood caries

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Key information

Conditions

Severe Early Childhood Caries

Age range

3 year–5 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Aslı Soğukpınar

Kahramanmaraş, Turkey (Türkiye)

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 3-5 years

Exclusion criteria

  • the children with systemic illness, using anti-inflammatory drug

Treatment and study plan

saliva cotton swab

Diagnostic Test

evaluate the role of thiol/disulfide homeostasis and oxidative stress in the saliva of children with severe early childhood caries and healthy group

Primary outcomes

  1. thiol/disulfide homeostasis

    Time frame: six months

    Unstimulated saliva samples were taken from all children. Then, thiol/disulfide homeostasis and antioxidant levels were evaluated.

Sponsors and collaborators

Lead sponsor

Kahramanmaras Sutcu Imam University

Other

Registry information

Official study title

Evaluation of Saliva Thiol/Disulfide Homeostasis and Oxidative Stress in Children With Severe Early Childhood Caries by a Novel Method- Part 1

Important dates

Study start
2020
Primary completion
2020
Study completion
2020
First posted
Dec 7, 2020
Registry last updated
Dec 7, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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