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Completed

NCT Number: NCT05679063

Therapeutic Exercise and Education in Neurophysiology of Pain in the Quality of Life of Women With Endometriosis

The objective of this study will be to evaluate treatment using ET exercise and pain education in women with endometriosis to achieve improvement in quality of life.

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Key information

Conditions

Endometriosis Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genital Diseases Genital Diseases, Female Urogenital Diseases

Age range

18 year–45 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

SBFisioterapia

Soria, 42001, Spain

About this study

A study will be carried out whose objective is to improve the quality of life in women with endometriosis through a program of therapeutic exercise and education in the neurophysiology of pain. Also as secondary variables will be observed: menstrual symptoms, sexual function, and abdominal wall thickness measured with ultrasound.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Women of reproductive age between 18 and 45 years.
  • Women with a medical diagnosis of endometriosis.
  • Women with visual analog scale (EVA) between 4 and 10 (moderate-severe pain) during the last 3 months in the suprapubic area, abdomen or perineum both continuously and intermittently.

Exclusion criteria

  • Women who must have surgery during the study.
  • Women who have undergone abdominal or pelvic surgery or who have given birth (vaginal or cesarean) in the last 6 months.
  • Women who are pregnant or planning a pregnancy.
  • Women with uncorrected pacemakers or coagulopathies, severe comorbid disorder, cancer (in the last 5 years or at present), severe mental disorders, or neuropathies affecting the nerves of the pelvis or lower extremities.
  • Physiotherapy treatments or treatments related to pathology or study areas 15 days prior to the beginning of the study.
  • Variations in medication in the 3 months prior to the start of the stud

Treatment and study plan

Physiotherapy

Other

A program of therapeutic exercise and education in the neurophysiology of pain will be applied to the participants of the experimental group

Sham, Control

Other

Talks about healthy habits

Primary outcomes

  1. Changes in quality of life perception assessed using EUROQuOL 5D - 5L

    Time frame: Baseline, Up to 1 month, Up to 3 months.

    The scale will be administered by one of the researchers, This scale covers five dimensions, each of which is assigned a score from 1 to 5, and with these scores, a code is obtained that indicates the person's quality of life. High values indicate poor quality of life.

Secondary outcomes

  1. Abdominal wall muscle thickness

    Time frame: Baseline, Up to 1 month, Up to 3 months

    The muscle thickness of the abdominal wall with ultrasound according to a defined protocol.

  2. Sexual Function assessed usinf Female Sexual Function Index (IFSF)

    Time frame: Baseline, Up to 1 month, Up to 3 months

    The scale will be administered by one of the researchers. This questionnaire consists of 19 questions and is grouped into six domains: desire, arousal, lubrication, orgasm, satisfaction, and pain; each question has 5 or 6 options, assigning them a score ranging from 0 to 5. The score for each domain is multiplied by a factor and the result final is the arithmetic sum of the domains. A higher score better sexuality

  3. Symptoms associated with menstruation assessed using CVM-22 (quality of life related to menstruation)

    Time frame: Baseline, up to 1 month, up to 3 months

    The scale will be administered by one of the researchers. Minimin value = 0. Maximum value = 66. A high result indicates a good quality of life-related to menstruation

Sponsors and collaborators

Lead sponsor

University of Valladolid

Other

Registry information

Official study title

Therapeutic Exercise and Education in Neurophysiology of Pain in the Quality of Life of Women With Endometriosis: Clinical Trial

Important dates

Study start
2022
Primary completion
2024
Study completion
2025
First posted
Jan 10, 2023
Registry last updated
Jun 4, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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