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OpenTrials
Completed

NCT Number: NCT04028739

Theracurmin vs Curcumin Bioavailability Study

A randomized, open-label, cross-over, single administration study to compare bioavailability of curcumin in health adults

Completed

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Key information

Conditions

Age range

19 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Korea Kuro Hospital

Seoul, South Korea

About this study

  • Randomization, Open-label, 3-period, 6-sequence, Crossover, Single
  • Drug-free inverval : more than 7 days
  • Sampling time : 0,0.5,1,1.5,2,3,4,6,8,12h

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy adult 19 to 60 years
  • BMI 18.0~30.0kg/m2 at screening
  • Subject who was given, and fully understood, the information about the study, and has provided voluntary written informed consent to participate in the study and agreed to comply with the study requirements.

Exclusion criteria

  • A person with clinically significant disease corresponding to cardiovascular, respiratory, liver, kidney, digestive system, blood/tumor system, endocrine system, immune system, neuropsychiatry or who has a history within the last 6 months.
  • A person with a history of gastrointestinal disease or surgery (except for simple cecal surgery or hernia surgery) that may affect the absorption of food for clinical research.
  • Persons who have an irritable reaction to foods containing turmeric or other drugs and food.
  • Those who took medicines within 7 days before the first intake of food for clinical research.
  • Food for Clinical Research If you have consumed foods containing turmeric (eg, radishes, curry) within 7 days before the first intake of food, or you can't consume until the day of intake of food for the last clinical study.
  • Those who have participated in other clinical studies within 90 days prior to the first intake of food for clinical research.
  • Women who are pregnant or lactating during screening, or who plan to become pregnant during clinical research. A person who is deemed unsuitable for participating in this clinical study because of other reasons.

Treatment and study plan

curmin

Dietary Supplement

curcumin 90mg/day cross-over

Other names: Theracurmin CR-033P, Theracurmin CR-031P, Curcumin

Primary outcomes

  1. Cmax

    Time frame: 12hours

    Maximum concentration at steady state

  2. AUC

    Time frame: 12hours

    Area under the concentration-time curve at steady state

Sponsors and collaborators

Lead sponsor

Handok Inc.

Industry

Registry information

Official study title

A Randomized, Open-label, Cross-over, Single Administration Study to Compare Bioavailability of Curcumin in Health Adults

Important dates

Study start
2019
Primary completion
2019
Study completion
2019
First posted
Jul 23, 2019
Registry last updated
Dec 6, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.