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Completed

NCT Number: NCT01074541

The Vitamin D Dose-Response Relationship

The purpose of the study is to determine the importance of the UV intensity and the UVB dose on the Vitamin D response after UVB.

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Key information

Conditions

Vitamin D Status Neoplasms Neoplasms by Site Skin Diseases Skin Neoplasms Skin and Connective Tissue Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Bispebjerg Hospital, Department of Dermatology

Copenhagen NV, NV, 2400, Denmark

About this study

The work is addressing vitamin D production after UVB exposure and explore the importance of UVB dose and UV intensity. Four different UVB doses and four different UV intensities are used to explore these relationships.

Many assumptions have been made concerning the vitamin D production after UVB exposure but only few studies exist.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18-65 years
  • Healthy

Exclusion criteria

  • Sun bed use
  • Holiday or business travel south of 45 degrees latitude during trial
  • Illness
  • Drug addiction
  • Pregnancy
  • Lactating

Treatment and study plan

UVB

Radiation

0.375 SED x 4 in a week

Other names: UVB radiation

Primary outcomes

  1. Vitamin D (nmol/l)

    Time frame: 2 days after exposure

    Vitamin D measured in a blood sample to define the dose-response relationship between UVB dose, UV intensity and Vitamin D production in the skin after UVB exposure.

Secondary outcomes

  1. Other parameters

    Time frame: 2 days after radiation

    To invesitage whether other parameters like sex, BMI, Diet etc. influences the vitamin D production after UVB exposure.

Sponsors and collaborators

Lead sponsor

Bispebjerg Hospital

Other

Collaborators

  • The Danish Medical Research Council

Registry information

Official study title

Vitamin D Production Depends on Ultraviolet-B Dose But Not on UV-intensity. A Randomized Controlled Trial

Important dates

Study start
2008
Primary completion
2008
Study completion
2010
First posted
Feb 24, 2010
Registry last updated
Feb 24, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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