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OpenTrials
Completed

NCT Number: NCT06825754

The Value of Serum MicroRNA-21-5p and LncRNAgadd7 Expression Levels in Predicting the Severity and Prognosis of ARDS ( Acute Respiratory Distress Syndrome )

By measuring the expression levels of MicroRNA-21-5p (miR-21-5p) and LncRNAgadd7 in the peripheral blood of ARDS patients, the study aims to explore the correlation between these levels and the severity and prognosis of ARDS.

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Key information

Conditions

Acute Respiratory Distress Syndrome Lung Diseases Respiration Disorders Respiratory Distress Syndrome Respiratory Tract Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Affiliated Hospital of Zunyi Medical University

Zunyi, Guizhou, 563100, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥ 18 years;
  • Meets the Berlin Criteria for ARDS;
  • Diagnosed with ARDS within 48 hours;
  • Signed informed consent.

Exclusion criteria

  • Immunosuppressed patients: including those on immunosuppressive drugs, history of stem cell transplantation, etc.;
  • Patients with malignant tumors;
  • Pregnant women;
  • Patients discharged from the ICU within 48 hours;
  • History of chronic lung diseases.

Treatment and study plan

Primary outcomes

  1. The expression levels of MicroRNA-21-5p (miR-21-5p)

    Time frame: 28 days

  2. the expression levels of LncRNAgadd7

    Time frame: 28 days

Sponsors and collaborators

Lead sponsor

Shao Yuekai

Other

Registry information

Important dates

Study start
2023
Primary completion
2024
Study completion
2025
First posted
Feb 13, 2025
Registry last updated
Feb 13, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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