The Use of Narrow Band Imaging in Screening Colonoscopy

Narrow band imaging (NBI) is an imaging technique that allows a better definition of capillary pattern and improves the contrast between adenomas and the surrounding mucosa. Conflicting data exist on the ability of NBI in to improve detection of colonic neoplasm; the impact of NBI is being tested in several screening scenarios. The investigators evaluated whether the routine use of NBI, compared to white light (WL), during the withdrawal phase of screening colonoscopy improved adenoma detection.

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Key information

Conditions

Colonoscopy

Age range

50 year–69 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

50-69 year-old asymptomatic subjects at average-risk of CRC
positive FOBT participating in a national mass-screening program and referred for colonoscopy

Exclusion criteria

ongoing anticoagulation therapy
inadequate bowel cleansing
incomplete colonoscopy
refusing to participate

Treatment and study plan

Narrow Band Imaging

Procedure

Narrow Band Imaging

Primary outcomes

Adenoma Detection

Time frame: duration of colonoscopy procedure

Detection of adenoma, defined as the number of patients with > 1 adenoma, under White Light or NBI visualization

Secondary outcomes

Detection of Flat and/or Depressed Adenomas

Time frame: duration of colonoscopy procedure

number of patients with at least 1 flat and/or depressed adenoma

Sponsors and collaborators

Lead sponsor

Valduce Hospital

Other

Registry information

Official study title

The Impact of Narrow Band Imaging in Screening Colonoscopy: a Randomized Controlled Trial.

Important dates

Study start: 2007
Primary completion: 2008
Study completion: 2008
First posted: May 27, 2009
Registry last updated: Apr 26, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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