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Completed

NCT Number: NCT00788645

The Use of a Forecasting System for Predicting Exacerbations of COPD

People with Chronic Obstructive Pulmonary Disease (COPD) often have periods during the year when their symptoms become worse. These are often due to an infection and are called "exacerbations" by doctors. Exacerbations are more common in the winter and also seem to be related to particular types of weather. As well as forecasting the weather the UK Met Office has developed a system to try to predict when exacerbations are likely to occur. The main purpose of this research study is to find out whether the Met Office forecasting service can predict when exacerbations are more likely to occur and whether the advice given during the predicted higher risk periods leads to fewer patients having an exacerbation or if it reduces the impact of the exacerbation. The study will also assess if there is a link between viral or bacterial infection and breathing problems that occur during the study period. The study will also collect information about possible causes of the breathing problems and what happens to the person afterwards. The results of this study will help us learn more about breathing problems which may lead to new research studies that would aim to improve the care of people with COPD.

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Key information

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Current or former smokers with a diagnosis of COPD
  • Having impaired lung function as measured by spirometry

Exclusion criteria

  • History of asthma or nasal symptoms caused by hayfever
  • No telephone
  • Inability to record symptoms in an electronic diary (PDA)

Treatment and study plan

COPD self care advice

Behavioral

Information leaflets on COPD and thermometers to monitor the ambient temperature in the bedroom and living room

Poor weather forecast warning

Behavioral

Interactive automated telephone service to contact patients prior to anticipated periods of poor weather

Primary outcomes

  1. The incidence and frequency of COPD exacerbations in each of the intervention groups

    Time frame: December 2008 to March 2009 inclusive

  2. Electronic diary symptoms using the EXACT instrument

    Time frame: Daily recording

Secondary outcomes

  1. Medication usage and hospital admissions

    Time frame: Acutely

  2. Changes in the St Georges Respiratory questionaire

    Time frame: Start and end of study period

  3. Severity and duration of exacerbations assessed using the EXACT instrument

    Time frame: Daily recording

Sponsors and collaborators

Lead sponsor

AstraZeneca

Industry

Registry information

Official study title

The Use of a Forecasting System for Predicting Exacerbations of COPD: Effect on Symptoms and Hospitalisation and Relevance of Viral Infections

Important dates

Study start
2008
Primary completion
2009
Study completion
2009
First posted
Nov 11, 2008
Registry last updated
Dec 2, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.