The UPbeating GReek Application of DancE in Parkinson's Disease Clinical Trial

Minimum score 0, Maximum score 100. A higher score indicates worse quality of life.

Minimum score 1, Maximum score 5. A higher score indicates more fatigue.

Minimum score 0, Maximum score 84. A higher score indicates more fatigue.

Minimum score 0, Maximum score 30. Lower scores indicate cognitive impairment.

Minimum score 0, Maximum score 56. Lower scores indicate worse balance.

Normal score 0-9, Mild score: 10-12, Moderate score: 13-20, Severe score: 21-27, and Extremely severe: 28-42

Normal score 0-6, Mild score: 7-9, Moderate score: 10-14, Severe score: 15-19, and Extremely severe: 20-42

Normal score 0-10, Mild score: 11-18, Moderate score: 19-26, Severe score: 27-34, and Extremely severe: 35-42

MDS-UPDRS has 4 parts. Part I assesses non-motor experiences of daily living (13 items, score range: 0-52), part II assesses motor experiences of daily living (13 items, score range: 0-52), part III assesses motor signs (33 items, score range: 0-132), and part IV assesses motor complications, dyskinesias and motor fluctuations (6 items, score range: 0-24). Each item score ranges from 0 (normal) to 4 (severe) and higher scores indicate a greater impact of Parkinson's disease signs.

SARC-F is a self-reporting screening tool for the assess of the sarcopenia risk and comprises five components: strength, assistance walking, rise from a chair, climb stairs, and number of falls (score range: 0-2 for each component, and 0-10 in total. Healthy status score range: 0-3, risk of sarcopenia score: ≥4).

According to EWGSOP2, sarcopenia is (a) probable to an individual with low muscle strength (hand grip strength for men: <27 kg, and women: <16 kg), (b) confirmed to an individual with the above criteria plus low muscle quantity (appendicular skeletal muscle mass index for men: <7 kg/m^2, and women: <5,5 kg/m^2), and (c) severe to an individual with the two above criteria plus low physical performance (4-m usual walking speed test ≤0.8 m/s). Hand grip strength will be assessed by a calibrated digital handheld dynamometer, appendicular muscle mass index by a bioelectrical impedance analysis (BIA) equipment, and physical performance by the 4-min usual walking speed test.

A score from the equation kg/m^2. Lower scores than 18,5 indicate underweight, scores of 18,5-24,9 indicate normal weight, scores of 25-29,9 indicate overweight and scores equal or over 30 indicate obesity. Within the obesity category 3 subcategories exist: Class I scores of 30-34, Class II scores of 35-39, and Class III scores of ≥40.

According to the Fried FP, 5 criteria have to be assessed: unintentional weight loss >5 kg the last year, weakness (handgrip strength for men: <27 kg, and women: <16 kg), slow walking speed (10-m usual walking speed test ≤0.8 m/s), exhaustion (PFS-16 total score ≥3, which indicates moderate-to-severe fatigue), and low levels of physical activity (International Physical Activity Questionnaire-Short Form/IPAQ-SF total score <600 MET-min-week^-1, which indicates inactivity). The FP score ranges from 0 to 5 (1 point for each criteria; 0: best score to 5: worst score). As frail defined an individual with a score of ≥3, as pre-frail an individual with a score of 1-2, and as non-frail or robust an individual with a score 0.

Music Preferences scale of Gardikiotis & Baltzis is a 6-point Likert scale (0: i don't know it, 1: i don't like it at all to 5: i like it very much) of 24 items (each item includes a different music genre) and evaluates the individual's level of preference to a variety of Greek and non-Greek music.

Occurence of adverse events comprising falls, injuries, muscle soreness or excessive fatigue, and emergent adverse events comprising death, life-threatening, hospitalization, persistent or significant disability, congenital anomaly/birth defect or necessity of surgical operation for any of the above.

Adherence and attrition rates; an adherence rate ≥70% is considered as high in elderly with functional limitations, and attrition rate ≤15% is considered acceptable by the PEDro scale.

Verbal statement for willingness to continue the program after the end of the intervention in a 6-point Likert scale (0: i don't know if i'd like to continue the program, 1: i don't want to continue the program at all to 5: i want to continue the program very much), and two open questions (I. Could you please list all the positive and negative points of the live DfPD® intervention? and II. Could you please list all the positive and negative points of the online DfPD® intervention?) in a 1-to-1 interview for each participant in the end of the program.

Target, up to 5 months for 40 participants.