Recruiting

NCT Number: NCT07371377

The TOF3D Mechanomyograph. Evaluation of a New Device for Assessment of the Neuromuscular Block.

In clinical anesthesiologic practice, most institutions use acceleromyography in order to assess the degree of a neuromuscular block.

The aim of the present study is to assess a new device using mechanomyography. Until recently, this method was reserved for experimental settings. It seems to be able to work more precisely, and additionally, it offers the opportunity to use other stimulation patterns than acceleromyographic measurements.

The investigation is divided into two parts:

Part 1 compares the mechanomyograph directly with an acceleromyograph. In part 2, two mechanomyographs using different stimulation patterns are compared with each other.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Mechanomyography Neuromuscular Blockade Monitoring

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Anesthesia and Intensive Care Medicine

Bad Hersfeld, 36251, Germany

Location status: Recruiting

Location contact

Stefan Soltesz, Professor

CONTACT

[email protected]

0049 173 3262086

Stefan Soltesz, Professor

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

patients scheduled for surgery requiring general anesthesia with neuromuscular blocking agents

Exclusion criteria

anticipated or known difficult airway
increased risk for aspiration
pregnancy
neuromuscular disorders

Treatment and study plan

measurement of the time course of a neuromuscular block

Device

a new device is compared to an established one.

Primary outcomes

difference in time to recovery to a train of four ratio of 1,0.

Time frame: from enrollment to the end of anesthesiologic treatment at the day of surgery (2-3 weeks after enrollment)

difference in time to recovery to a train of four ratio of 1,0 measured by acceleromyography and mechanomyography, respectively

Study contacts

Contact information is provided by the study sponsor or research team.

Stefan Soltesz, Professor

CONTACT

[email protected]

0049 6621 88 922775

Sponsors and collaborators

Lead sponsor

Klinikum Hersfeld-Rotenburg

Other

Registry information

Acronym: MMG versus AMG

Important dates

Study start: 2026
Primary completion: 2026
Study completion: 2027
First posted: Jan 27, 2026
Registry last updated: Jan 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting