The Time of Positive Conversion of Interferon-γ Releasing Assay After Tuberculosis Exposure

The aim is to evaluate the time of positive conversion after exposure to smear positive pulmonary tuberculosis (TB) in a platoon of Korean military, a closed communal setting.

Completed

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Key information

Conditions

Tuberculosis Actinomycetales Infections Bacterial Infections Bacterial Infections and Mycoses Gram-Positive Bacterial Infections Infections Mycobacterium Infections

Sex eligibility

Male

Study type

Observational

About this study

In a platoon where TB outbreak occurred, we performed low dose chest CT (LDCT), QuantiFERON-TB gold in tube (QFT) and two-step (0, 4weeks) TST for outbreak investigation. We perform QFT at 0, 2, 4, 8 and 12 weeks after initial investigation for soldiers with negative QFT results, and soldiers with positive QFT and normal LDCT took isoniazid and rifampin for 3 months as treatment of latent TB.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All soldiers who assigned to the military platoon where a tuberculosis outbreak occurred

Exclusion criteria

Soldiers who could not complete study or refused the study protocol

Sponsors and collaborators

Lead sponsor

Armed Forces Capital Hospital, Republic of Korea

Other Gov

Registry information

Important dates

Study start: 2009
Primary completion: 2010
Study completion: 2010
First posted: Sep 22, 2009
Registry last updated: Apr 8, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed