The Thai Red Cross Society Prevention of Mother-To-Child Transmission of HIV (TRCS PMTCT) Program

• To describe characteristics of HIV-infected pregnant women who request HAART from the Thai Red Cross Society PMTCT (TRCS PMTCT) program
• To study adverse pregnancy outcomes among HIV-infected pregnant women who receive HAART
• To study adverse events in infants born to women who receive HAART during pregnancy
• To evaluate risk factors for HAART-related toxicities and for perinatal HIV transmission
• To establish the pilot model of care for HIV-infected pregnant women in middle income country

Inclusion criteria

Volunteers meeting all of the following criteria will be considered eligible for enrollment in the study:

• HIV-infected pregnant women (as defined by the hospital)
• Choose to start HAART according to protocol and do not want to receive antiretroviral treatment provided by the other health care systems
• Understand the study and sign informed consent form. Persons who cannot read will have the consent form read to them by a study staff and they can give informed consent by using thumb print.
• Availability for follow-up for the planned study duration

Exclusion criteria

Volunteers meeting any of the following criteria will be excluded from the study:

1.Persons who have a history of a medical or psychiatric disorder by interview and physical examination according to standard practices, that in the judgment of the treating physician, would interfere with or serve as a contraindication to adherence to the study protocol or ability to give informed consent.